What Happens If Precancers Go Untreated
As the name suggests, precancers are damaged skin cells that arent considered cancerous, but if they are left untreated, these lesions are at high risk to become skin cancer. There are two main types of precancerous skin conditions: actinic keratosis and dysplastic nevi. Actinic keratosis looks like a rough, scaly patch of the skin that is usually red or brown. This condition may develop into squamous cell carcinoma if left untreated.
Nevi are moles, and dysplastic nevi is a term that means a mole is abnormal. Dysplastic nevi may develop into melanoma without proper treatment. While precancerous skin cancers are not malignant on their own, the potential to develop into life-threatening forms of this condition means they need to be evaluated regularly.
Risks Associated With Untreated Squamous Cell Carcinoma
Squamous cell carcinoma is the second most common type of skin cancer. This type of cancer has a variable growth rate. Some squamous cell carcinomas grow slowly, while others can grow rapidly. Smaller squamous cell carcinomas have a lower risk of metastasis, however, if they are large, they are at higher risk for spreading to other organs, including the lymph nodes. In certain locations, such as the ear, lip, and temple, there is a higher risk of spread as well. As with all skin cancers, treatment in earlier stages is always recommended to prevent cancer from spreading. Squamous cell carcinomas can be life-threatening if left untreated.
According to Dr. Truong, We recommend patients keep a close eye on any changes to their skin color, texture, or sensation by completing self-exams at home every month or every other month. With squamous cell carcinoma, the first thing patients notice is red, rough, and scaly patches of skin. This type of skin cancer can be asymptomatic, but can also be painful to the touch. Some patients experience abnormal sensations in the areas . The feelings of pain and numbness may be the first sign that squamous cell carcinoma is spreading and impacting surrounding nerves, therefore it is important to let your dermatologist know if you are experiencing these symptoms.
Can Squamous Cell Carcinoma Be Prevented Or Avoided
Most cases of squamous cell carcinoma can be prevented by avoiding exposure to UV rays.
- Avoid the sun, especially during peak hours of 10 a.m. to 4 p.m.
- Use sunscreen, even on cloudy days.
- Wear a wide-brimmed hat, protective clothing, and sunglasses when you go outside.
- Avoid places that reflect light, such as water, sand, or concrete.
- Dont try to get a tan, including using tanning beds or sunlamps.
If squamous cell carcinoma is caught early, it is usually easy to treat. Examine your skin once a month. See your family doctor right away if you find anything that looks suspicious.
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Squamous Cell Carcinoma Causes
Exposure to ultraviolet rays, like the ones from the sun or a tanning bed, affects the cells in the middle and outer layers of your skin and can cause them to make too many cells and not die off as they should. This can lead to out-of-control growth of these cells, which can lead to squamous cell carcinoma.
Other things can contribute to this kind of overgrowth, too, like conditions that affect your immune system.
Tests Or Procedures That Examine The Skin Are Used To Diagnose Basal Cell Carcinoma And Squamous Cell Carcinoma Of The Skin
The following procedures may be used:
- Physical exam and health history: An exam of the body to check general signs of health, including checking for signs of disease, such as lumps or anything else that seems unusual. A history of the patients health habits and past illnesses and treatments will also be taken.
- Skin exam: An exam of the skin for bumps or spots that look abnormal in color, size, shape, or texture.
- Skin biopsy: All or part of the abnormal-looking growth is cut from the skin and viewed under a microscope by a pathologist to check for signs of cancer. There are four main types of skin biopsies:
- Shave biopsy: A sterile razor blade is used to shave-off the abnormal-looking growth.
- Punch biopsy: A special instrument called a punch or a trephine is used to remove a circle of tissue from the abnormal-looking growth. Enlarge Punch biopsy. A hollow, circular scalpel is used to cut into a lesion on the skin. The instrument is turned clockwise and counterclockwise to cut down about 4 millimeters to the layer of fatty tissue below the dermis. A small sample of tissue is removed to be checked under a microscope. Skin thickness is different on different parts of the body.
- Incisional biopsy: A scalpel is used to remove part of a growth.
- Excisional biopsy: A scalpel is used to remove the entire growth.
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What Survival Rates Mean
The survival rate is the percentage of people who live for a certain period of time with this cancer. The number is based on research done on large groups of people with the same stage of cancer.
Experts dont know the exact survival numbers for late-stage SCC, because cancer registries dont track statistics for this cancer. However, your doctor may be able to give you an estimate of your prognosis.
When it comes to surviving cancer, everyone is different. Your outcome will depend on the specific treatments you have and how well you respond to them. Talk to your doctor about your outlook and what it means.
Metastatic Squamous Cell Carcinoma
Squamous cell carcinoma – a very common form of nonmelanoma skin cancer that originates in the squamous cells – becomes metastatic when it spreads beyond the primary cancer site and affects other areas of the body. Metastatic squamous cell carcinoma is uncommon but can develop if the primary cancer is not surgically removed or treated in a timely manner.
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If The Cancer Comes Back
If your cancer does come back at some point, your treatment options will depend on where the cancer is and what treatments youve had before. If the cancer comes back just on the skin, options might include surgery, radiation therapy, or other types of local treatments. If the cancer comes back in another part of the body, other treatments such as targeted therapy, immunotherapy, or chemotherapy might be needed. For more general information on dealing with a recurrence, see our Recurrence section.
What Causes A Squamous Cell Carcinoma
The most important cause is too much exposure to ultraviolet light from the sun or other sources. This can cause the DNA of skin cells in the outer layer of the skin to change. Sometimes this alteration in DNA allows the skin cells to grow out of control and develop into an SCC. Ultraviolet light damage can cause SCC directly, or sometimes it can induce a scaly area called an actinic keratosis or Bowens disease. These can change into SCC if they are not treated.
Squamous cell carcinomas can also develop in skin damaged by other forms of radiation, in burns and persistent chronic ulcers and wounds and in old scars. Certain human viral wart viruses can also be a factor. However, SCC itself is not contagious.
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Basal Cell Carcinoma Squamous Cell Carcinoma Of The Skin And Actinic Keratosis Often Appear As A Change In The Skin
Not all changes in the skin are a sign of basal cell carcinoma, squamous cell carcinoma of the skin, or actinic keratosis. Check with your doctor if you notice any changes in your skin.
Signs of basal cell carcinoma and squamous cell carcinoma of the skin include the following:
- A sore that does not heal.
- Areas of the skin that are:
- Raised, smooth, shiny, and look pearly.
- Firm and look like a scar, and may be white, yellow, or waxy.
- Raised and red or reddish-brown.
- Scaly, bleeding, or crusty.
Basal cell carcinoma and squamous cell carcinoma of the skin occur most often in areas of the skin exposed to the sun, such as the nose, ears, lower lip, or top of the hands.
Signs of actinic keratosis include the following:
- A rough, red, pink, or brown, scaly patch on the skin that may be flat or raised.
- Cracking or peeling of the lower lip that is not helped by lip balm or petroleum jelly.
Actinic keratosis occurs most commonly on the face or the top of the hands.
Risks Associated With Untreated Basal Cell Carcinoma
Basal cell carcinoma is the most common form of skin cancer. Its also the slowest growing of the common forms of skin cancer and the least likely to metastasize, meaning it rarely spreads to other parts of the body. However, basal cell carcinoma presents a risk for disfigurement if left untreated. Without proper intervention, basal cell carcinoma can grow and invade local structures. Additionally, these lesions may present a risk for ulceration , bleeding, and infection. The type of treatment available in the early stages is likely to be more effective, less invasive, and more cost-effective. The longer basal cell carcinoma goes untreated, the procedures necessary to remove it become more advanced, invasive, and costly.
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Diagnosing Squamous Cell Carcinoma
The main way to diagnose squamous cell carcinoma is with a biopsy. This involves having a small piece of tissue removed from the suspicious area and examined in a laboratory.
In the laboratory, a pathologist will examine the tissue under a microscope to determine if it is a skin cancer. He or she will also stage the cancer by the number of abnormal cells, their thickness, and the depth of penetration into the skin. The higher the stage of the tumor, the greater the chance it could spread to other parts of the body.
Squamous cell carcinoma on sun-exposed areas of skin usually does not spread. However, squamous cell carcinoma of the lip, vulva, and penis are more likely to spread. Contact your doctor about any sore in these areas that does not go away after several weeks.
Can Squamous Cell Cancer Be Cured
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Staging For Basal Cell Carcinoma And Squamous Cell Carcinoma Of The Skin Depends On Where The Cancer Formed
Staging for basal cell carcinoma and squamous cell carcinoma of the eyelid is different from staging for basal cell carcinoma and squamous cell carcinoma found on other areas of the head or neck. There is no staging system for basal cell carcinoma or squamous cell carcinoma that is not found on the head or neck.
Surgery to remove the primary tumor and abnormal lymph nodes is done so that tissue samples can be studied under a microscope. This is called pathologic staging and the findings are used for staging as described below. If staging is done before surgery to remove the tumor, it is called clinical staging. The clinical stage may be different from the pathologic stage.
How To Improve Your Odds
Even if youve exhausted all of your treatment options, you dont have to give up. Researchers are always testing new SCC treatments in clinical trials. Getting into one of these studies could give you access to a drug or therapy that might slow or stop your cancer.
To avoid the worsening of your skin cancer or a new cancer in a different area, protect yourself from the suns damaging UV rays. Wear sun-protective clothing and a wide-brimmed hat whenever you go outdoors. Apply a layer of broad-spectrum sunscreen that protects against both UVA and UVB rays.
Also check your own skin for any new growths on a regular basis. Report any skin changes to your doctor right away.
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What Is Squamous Cell Carcinoma
Squamous cell carcinoma is the second most common form of skin cancer. Its usually found on areas of the body damaged by UV rays from the sun or tanning beds. Sun-exposed skin includes the head, neck, chest, upper back, ears, lips, arms, legs, and hands.
SCC is a fairly slow-growing skin cancer. Unlike other types of skin cancer, it can spread to the tissues, bones, and nearby lymph nodes, where it may become hard to treat. When caught early, its easy to treat.
SCC can show up as:
- A dome-shaped bump that looks like a wart
- A red, scaly patch of skin thats rough and crusty and bleeds easily
- An open sore that doesnt heal completely
- A growth with raised edges and a lower area in the middle that might bleed or itch
What Is Skin Cancer
Cancer can start any place in the body. Skin cancer starts when cells in the skin grow out of control.
Skin cancer cells can sometimes spread to other parts of the body, but this is not common. When cancer cells do this, its called metastasis. To doctors, the cancer cells in the new place look just like the ones from the skin.
Cancer is always named based on the place where it starts. So if skin cancer spreads to another part of the body, its still called skin cancer.
The skin
Cancer can spread through tissue, the lymph system, and the blood:
- Tissue. The cancer spreads from where it began by growing into nearby areas.
- Lymph system. The cancer spreads from where it began by getting into the lymph system. The cancer travels through the lymph vessels to other parts of the body.
- Blood. The cancer spreads from where it began by getting into the blood. The cancer travels through the blood vessels to other parts of the body.
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What Are The Signs And Symptoms Of Squamous Cell Carcinoma
SCC signs and symptoms include skin changes like:
- A rough-feeling bump or growth which might then crust over and bleed.
- A growth that is higher than the skin but has a depression in the middle.
- A sore that will not heal, or a sore that heals and then comes back.
- A piece of skin that is flat, is scaly and red.
- A precancerous growth called actinic keratosis, which is a bump or lump that can feel dry, itchy, scaly, or be discolored.
- A precancerous skin lesion called actinic cheilitis, which happens mainly on the lower lip. The tissue becomes pale, dry, and cracked.
- A precancerous condition called leukoplakia, in which white spots develop in the mouth, on the tongue, gums, or cheeks
Effective Options For Early Stage Scc
Most squamous cell carcinomas of the skin can be cured when found and treated early. Treatment should happen as soon as possible after diagnosis, since more advanced SCCs of the skin are more difficult to treat and can become dangerous, spreading to local lymph nodes, distant tissues and organs. Find out more about treatment options for advanced or recurring SCCs here.
If youve been diagnosed with an SCC that has not spread, there are several effective treatments that can usually be performed on an outpatient basis. The choices available to you depend on the tumor type, size, location and depth, as well as your age and overall health.
Options include:
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Factors Affecting Squamous Cell Carcinoma Prognosis
There are a handful of factors that can affect a patients prognosis, including:
- Having a weakened immune system
- The location of the tumortumors found on the face, scalp, fingers and toes spread more easily, as do tumors that arise in an open wound
- If the cancer has recurred
- Larger tumors and those that are growing deep in the skin
Screening For Skin Cancer
While early detection and treatment of skin cancer can improve patient outcomes,4 convincing data regarding the benefit of mass screening programs are lacking.5 In addition, the ability to identify potentially malignant lesions varies with physician training.6 Thus, except for very high-risk persons with a history of skin cancer or atypical mole syndrome, for whom periodic screening is universally recommended, there is considerable debate about who should be screened, who should perform the screening and how often screening should be performed .7 Part of the screening process should include an assessment of patient risk .1,812
Skin Cancer Screening Recommendations from Various Organizations
American Academy of Dermatology Skin Cancer Foundation and American Cancer Society
*Available at www.aafp.org/policy/camp/app-dc.html.
Information from Public Health Service. Office of Disease Prevention and Health Promotion. Clinician’s handbook of preventive services. Washington, D.C.: U.S. Department of Health and Human Services, 1994:155.
Skin Cancer Screening Recommendations from Various Organizations
American Academy of Dermatology Skin Cancer Foundation and American Cancer Society
*Available at www.aafp.org/policy/camp/app-dc.html.
Information from Public Health Service. Office of Disease Prevention and Health Promotion. Clinician’s handbook of preventive services. Washington, D.C.: U.S. Department of Health and Human Services, 1994:155.
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Can You Die From Basal Cell Carcinoma
Death from either basal cell or squamous cell cancers is quite rare. Statistics for these types of skin cancer arent tracked by cancer registries, so its difficult to have specific numbers, but its thought that less than 2,000 people in the U.S. die from both basal cell and squamous cell carcinomas each year.
These deaths are predominantly in elderly people who have not had their skin checked in a long time and cancer has grown quite large.
Considering there are over 4 million diagnosed cases of basal cell carcinoma each year in the U.S. , the risk of death from this form of skin cancer is quite low.