Different Types Of Cancer Start In The Skin
Skin cancer may form in basal cells or squamous cells. Basal cell carcinoma and squamous cell carcinoma are the most common types of skin cancer. They are also called nonmelanoma skin cancer. Actinic keratosis is a skin condition that sometimes becomes squamous cell carcinoma.
Melanoma is less common than basal cell carcinoma or squamous cell carcinoma. It is more likely to invade nearby tissues and spread to other parts of the body.
This summary is about basal cell carcinoma, squamous cell carcinoma of the skin, and actinic keratosis. See the following PDQ summaries for information on melanoma and other kinds of cancer that affect the skin:
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What To Look For
Any new spots that appear on the skin could potentially be skin cancer, considering that one in five people will develop at least one skin cancer in their lifetime. Definitively distinguishing the different types of skin cancer requires a biopsy and microscopic evaluation, but the general appearance of these tumors also differs to some degree.
- Basal cell carcinomas are often shiny and have been described as “pearlescent.” They may be flat, raised, or dome-shaped, and are often pink, pale, or flesh-colored. On careful inspection, tiny blood vessels may be visible when compared with the surrounding skin. Basal cell cancer characteristically is very often ulcerated and has been called a rodent ulcer because it looks like a mouse has gnawed it.
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- Squamous cell carcinomas are often raised and feel crusty to touch. They can appear scaly and may be ulceratedthat is, have a central depression that is lighter and flatter than the surrounding area. These cancers sometimes bleed, ooze, or form scabs.
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Melanoma Can Be Tricky
Identifying a potential skin cancer is not easy, and not all melanomas follow the rules. Melanomas come in many forms and may display none of the typical warning signs.
Its also important to note that about 20 to 30 percent of melanomas develop in existing moles, while 70 to 80 percent arise on seemingly normal skin.
Amelanotic melanomas are missing the dark pigment melanin that gives most moles their color. Amelanotic melanomas may be pinkish, reddish, white, the color of your skin or even clear and colorless, making them difficult to recognize.
Acral lentiginous melanoma, the most common form of melanoma found in people of color, often appears in hard-to-spot places, including under the fingernails or toenails, on the palms of the hands or soles of the feet.
The takeaway: Be watchful for any new mole or freckle that arises on your skin, a sore or spot that does not heal, any existing mole that starts changing or any spot, mole or lesion that looks unusual.
Acral lentiginous melanoma is the most common melanoma found in people of color.
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What Are The Symptoms Of Skin Cancer
Talk to your doctor if you notice changes in your skin such as a new growth, a sore that doesnt heal, a change in an old growth, or any of the A-B-C-D-Es of melanoma.
A change in your skin is the most common sign of skin cancer. This could be a new growth, a sore that doesnt heal, or a change in a mole.external icon Not all skin cancers look the same.
For melanoma specifically, a simple way to remember the warning signs is to remember the A-B-C-D-Es of melanoma
- A stands for asymmetrical. Does the mole or spot have an irregular shape with two parts that look very different?
- B stands for border. Is the border irregular or jagged?
- C is for color. Is the color uneven?
- D is for diameter. Is the mole or spot larger than the size of a pea?
- E is for evolving. Has the mole or spot changed during the past few weeks or months?
Talk to your doctor if you notice changes in your skin such as a new growth, a sore that doesnt heal, a change in an old growth, or any of the A-B-C-D-Es of melanoma.
The Different Types Of Skin Cancer: Melanoma Vs Non
The first thing to note when youre looking for early signs of skin cancer is that there is a distinction between melanoma and non-melanoma strains of the disease.
Non-melanoma skin cancers are the most common, and they begin within the deeper layers of your skin, which means that you might not notice any symptoms straight away. Melanoma cancers, on the other hand, are distinctly more dangerous and occur within the upper and middle layers of the skin.
Melanoma cancers are more aggressive because they can often spread to other parts of the body, leading to a more comprehensive disease. Both types of skin cancer can occur anywhere on the body, but they often appear most on areas frequently exposed to the sun.
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Flat Red Patches And Rashes
One type of cancer that affects the skin, T-cell lymphoma, often begins with very itchy, flat, red patches and plaques that are easily mistaken for eczema or psoriasis.
One type of T-cell lymphoma, mycosis fungoids, transitions from these patches to dome-shaped nodules, and then to extensive reddened areas on multiple areas of the body. It may spread to lymph nodes and other regions of the body such as the lungs, liver, and bones. T-cell lymphomas most often begin on the buttocks, groin, hips, armpits, and chest.
Other cancers, such as breast cancer, may spread to the skin and initially be mistaken for a benign rash. Inflammatory breast cancer is a type of breast cancer that originates in the skin and appears, at first, to be an eczematous type of rash.
The Abcdes Of Melanoma
The first five letters of the alphabet are a guide to help you recognize the warning signs of melanoma.
A is for Asymmetry. Most melanomas are asymmetrical. If you draw a line through the middle of the lesion, the two halves dont match, so it looks different from a round to oval and symmetrical common mole.
B is for Border. Melanoma borders tend to be uneven and may have scalloped or notched edges, while common moles tend to have smoother, more even borders.
C is for Color. Multiple colors are a warning sign. While benign moles are usually a single shade of brown, a melanoma may have different shades of brown, tan or black. As it grows, the colors red, white or blue may also appear.
D is for Diameter or Dark. While its ideal to detect a melanoma when it is small, its a warning sign if a lesion is the size of a pencil eraser or larger. Some experts say it is also important to look for any lesion, no matter what size, that is darker than others. Rare, amelanotic melanomas are colorless.
E is for Evolving. Any change in size, shape, color or elevation of a spot on your skin, or any new symptom in it, such as bleeding, itching or crusting, may be a warning sign of melanoma.
If you notice these warning signs, or anything NEW, CHANGING or UNUSUAL on your skin see a dermatologist promptly.
A is for Asymmetry
D is for Diameter or Dark
E is for Evolving
E is for Evolving
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What Do The Results Mean
If a mole or other mark on your skin looks like it might be a sign of cancer, your provider will probably order another test, called a skin biopsy, to make a diagnosis. A skin biopsy is a procedure that removes a small sample of skin for testing. The skin sample is looked at under a microscope to check for cancer cells. If you are diagnosed with skin cancer, you can begin treatment. Finding and treating cancer early may help prevent the disease from spreading.
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The Early Stages Of Skin Cancer
Some forms of cancer, especially melanoma, may appear suddenly and without warning. Most people become alarmed only when they develop a crust or sore that refuses to heal. Did you know that the early stages of cancer do not always look or feel so bad? Harmless-looking moles, skin lesions, or unusual skin growths may also be the signs of early stages.
Regular skin examination can help you spot these early clues. If you see anything suspicious or observe unusual appearances in your skin, we can help you get the right diagnosis and treatment immediately. Some forms of cancer in the skin can be life-threatening and spread without being given urgent attention.
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What Questions Should I Ask My Healthcare Provider
Questions to ask your dermatologist may include:
- What type of skin cancer do I have?
- What stage is my skin cancer?
- What tests will I need?
- Whats the best treatment for my skin cancer?
- What are the side effects of that treatment?
- What are the potential complications of this cancer and the treatment for it?
- What outcome can I expect?
- Do I have an increased risk of additional skin cancers?
- How often should I be seen for follow-up checkups?
What Is My Skin Type
Skin types that are more sensitive to ultraviolet radiation burn more quickly and are at a greater risk of skin cancer.
All skin types can be damaged by too much UV radiation. Skin types that are more sensitive to UV radiation burn more quickly and are at a greater risk of skin cancer.
People with naturally very dark skin still need to take care in the sun even though they may rarely, if ever, get sunburnt. The larger amount of melanin in very dark skin provides natural protection from UV radiation. This means the risk of skin cancer is lower.
Eye damage can occur regardless of skin type. High levels of UV radiation have also been linked to harmful effects on the immune system.
Vitamin D deficiency may be a greater health concern for people with naturally very dark skin, as it is more difficult for people with this skin type to make vitamin D.
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How To Check Yourself For Skin Cancer
The SCF recommends that people conduct skin self-exams at least once a month or more if you have risk factors such as an inherited gene that predisposes toward skin cancer, or if you have spent a lot of time in the sun.
This check, which should be done in a well-lit room with a floor-length mirror and a hand mirror, should not take long once you get the hang of it.
Youll need to examine every inch of your skin, from your scalp to the bottoms of your feet and nails. A self-exam body map can help keep track of whats normal for you and whats not.
The more often you do these self-exams, the more familiar you will be with every freckle, mole, sore, lump, and blemish on your body and the better you will be at recognizing potential trouble in the form of new markings or changes in the size, shape, or color of existing spots.
Overall, heres the bottom line on what you should be looking for, according to the American Academy of Dermatology : a mole or skin lesion that changes in size, shape, or color, as well as spots that itch or bleed. Also watch for a new growth or a sore that doesnt heal.
Knowing your body and all of its unique spots is the first step in knowing what to look for when it comes to early signs and symptoms of skin cancer.
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Can You Die From Skin Cancer On Your Head
Yes. You can die from untreated skin cancer on your head.
However, do not panic yet. Most skin cancer on the head or skin cancer on the scalp is highly treatable, especially during the early stages.
If you are still in the earliest stages of treatment, such as for Stage I melanoma, there is a low risk of metastasis or recurrence.
According to Healthline and other sources, the five-year survival rate for the earliest stages of melanoma on the scalp is as high as 97%.
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Spotting The Signs Of Squamous Cell Carcinoma
The second most common form of skin cancer, squamous cell carcinoma tends to occur more in light-skinned people, though dark-skinned people are also susceptible. Watch out for these signs:5 6 7
- Thick, rough, scaly patches of skin
- Red patches, growths, or lumps
- Wart-like appearance
- Open sores with a crusted surface and a raised border
- Hard horny cap on the bump
- Scaly appearance
- Very tender to the touch and bleeding easily if you scratch or bump them
Determining If The Cancer Has Spread
As part of your diagnosis, your doctor will also determine what stage the cancer is in. The different stages refer to whether and how far the cancer has spread in your body, on a Roman numeral scale of I to IV. A stage I cancer is small and contained to the body part where it originated, whereas a stage IV cancer has spread aggressively to other parts of the body.
Depending on the type of skin cancer that a person has, it may be more or less likely that it has spread through the body. For instance, basal cell skin cancer rarely spreads beyond the skin where it starts. However, melanomas and large squamous cell carcinomas are more likely to spread into other regions of the body. Cases of melanoma, in particular, may call for further tests to determine the specific stage theyre in.
Your doctor may evaluate multiple factors in order to stage the cancer. Using biopsies and imaging tests, your doctor may take a look at:
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The size and thickness of the tumor, and whether it has grown into surrounding tissues
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Nearby lymph nodes, to check for signs of cancer spread
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How To Spot A Bcc: Five Warning Signs
Check for BCCs where your skin is most exposed to the sun, especially the face, ears, neck, scalp, chest, shoulders and back, but remember that they can occur anywhere on the body. Frequently, two or more of these warning signs are visible in a BCC tumor.
Please note: Since not all BCCs have the same appearance, these images serve as a general reference to what basal cell carcinoma looks like.
An open sore that does not heal
A reddish patch or irritated area
A small pink growth with a slightly raised, rolled edge and a crusted indentation in the center
A shiny bump or nodule
A scar-like area that is flat white, yellow or waxy in color
Red Flags For Squamous Cell Carcinoma
Like basal cell cancer, squamous cell cancer tends to develop on parts of the body that get a lot of sun, such as the face, neck, ear, lip, and back of the hands.
It might also appear in scars or skin sores anywhere on the body
While squamous cell carcinoma can look like a flat area closely resembling healthy skin, there may be clearer signs of malignancy, according to the SCF, including:
- Rough or scaly red patches that may bleed or crust
- Raised growths or lumps, sometimes with a depression in the center
- Open sores, possibly with oozing or crusted areas, that dont heal or that go through cycles of healing and bleeding
- Growths that resemble warts
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What Are Some Of The Lesser
Some of the less common skin cancers include the following:
Kaposi sarcoma is a rare cancer most commonly seen in people who have weakened immune systems, those who have human immunodeficiency virus /AIDS and people who are taking immunosuppressant medications who have undergone organ or bone marrow transplant.
Signs and symptoms of Kaposi sarcoma are:
- Blue, black, pink, red or purple flat or bumpy blotches or patches on your arms, legs and face. Lesions might also appear in your mouth, nose and throat.
Merkel cell carcinoma
Merkel cell carcinoma is a rare cancer that begins at the base of the epidermis, the top layer of your skin. This cancer starts in Merkel cells, which share of the features of nerve cells and hormone-making cells and are very close to the nerve ending in your skin. Merkel cell cancer is more likely to spread to other parts of the body than squamous or basal cell skin cancer.
Signs and symptoms of Merkel cell carcinoma are:
- A small reddish or purplish bump or lump on sun-exposed areas of skin.
- Lumps are fast-growing and sometimes open up as ulcers or sores.
Sebaceous gland carcinoma
Sebaceous gland carcinoma is a rare, aggressive cancer that usually appears on your eyelid. This cancer tends to develop around your eyes because theres a large number of sebaceous glands in that area.
Signs and symptoms of sebaceous gland carcinoma are:
- A painless, round, firm, bump or lump on or slightly inside your upper or lower eyelid.
Dermatofibrosarcoma protuberans