What Are The Risk Factors For Basal Cell Carcinoma
Basal cell carcinoma, squamous cell carcinoma and melanoma are all skin cancers caused by exposure to damaging ultraviolet raysfrom natural and artificial sunlight. There’s also a genetic condition called basal cell nevus or Gorlin syndrome, which can cause people to develop hundreds of basal cell skin cancers, but it’s extremely rare, says Dr. Christensen.
People at the highest risk for basal cell carcinoma tend to have fair or light-colored skin, a history of sun exposure and a tendency to sunburn quickly. Fair-skinned people have a 50 percent risk of developing basal skin cancer at some point in their lives, Dr. Christensen says. The cancer is the result of cumulative damage of years spent in the sun, and may take 20 years to manifest.
Although it’s often more common in older people, it can occur in younger adults, too.
Basal cell carcinoma spreads very slowly and very rarely will metastasize, Dr. Christensen says. But if it’s not treated, basal cell carcinoma can continue to grow deeper under the skin and cause significant destruction to surrounding tissues. It can even become fatal. For example, an untreated basal cell carcinoma on the face can grow into the bones and, over time, directly into the brain, Dr. Christensen says.
Leaving Squamous Cell Carcinoma Untreated
The third type of skin cancer we have to be cautious of in Australia is squamous cell carcinoma. This is potentially life threatening and is most dangerous when found on the face, lips, ears or neck. As it grows, there is the chance it may spread to the lymph nodes and internal organs, and while it isnt as fast growing as melanoma, it still requires treatment.
You may notice squamous cell carcinoma in the top layer of your skin and it will likely be red and scaly. Surgery is often used for removal, but if it has progressed significantly some reconstruction to the face may be needed. This is the second most common form of skin cancer, and can be quite painful to touch.
All skin cancer has the potential to be fatal, and regular checks and any necessary treatment is recommended. Melanoma is by far the most serious form of skin cancer, and if suspected you should seek an urgent skin check. Please contact My Skin Centre to book your appointment in the Perth region.
Squamous Cell Carcinoma: Common In Sun
Squamous cell carcinoma, also called squamous cell cancer, is the second most common type of skin cancer. It accounts for about 20 percent of cases.
This type of cancer starts in flat cells in the outer part of the epidermis. It commonly crops up on sun-exposed areas, such as the face, ears, neck, lips, and hands. It can also develop on scars or chronic sores.
Squamous cell carcinomas may develop from precancerous skin spots, known as actinic keratosis .
These cancers might look like:
- A firm, red bump
- A flat lesion with a scaly, crusted surface
- A sore that heals and then reopens
People with lighter skin are more at risk for developing squamous cell carcinoma, but the skin cancer can also affect those with darker skin.
Other risk factors include:
- Having light eyes, blond or red hair, or freckles
- Being exposed to the sun or tanning beds
- Having a history of skin cancer
- Having a history of sunburns
- Having a weakened immune system
- Having the genetic disorder xeroderma pigmentosum
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Prognosis For Skin Cancer
It is not possible for a doctor to predict the exact course of a disease. However, your doctor may give you the likely outcome of the disease. If detected early, most skin cancers are successfully treated.
Most non-melanoma skin cancers do not pose a serious risk to your health but a cancer diagnosis can be a shock. If you want to talk to someone see your doctor. You can also call Cancer Council 13 11 20.
Squamous Cell Carcinoma Treatment
Squamous cell carcinoma can usually be treated with minor surgery that can be done in a doctors office or hospital clinic. Depending on the size and location of the SCC, your doctor may choose different techniques to remove it.
For small skin cancers:
- Curettage and electrodessication : removing the top layer of the skin cancer then using an electronic needle to kill cancer cells
- Laser therapy: an intense light destroys the growth
- : a photosensitizing solution applied to your skin then activated with a light or daylight, or sometimes with intense pulsed light
- Cryosurgery: freezing of the spot using liquid nitrogen
For larger skin cancers:
- Excision: cutting out the cancer spot and some healthy skin around it, then stitching up the wound
- Mohs surgery: excision and then inspecting the excised skin using a microscope; this requires stitching up the wound
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Biological Therapies And Melanoma
Biological therapies are treatments using substances made naturally by the body. Some of these treatments are called immunotherapy because they help the immune system fight the cancer, or they occur naturally as part of the immune system.;There are many biological therapies being researched and trialled, which in the future may help treat people with melanoma. They include monoclonal antibodies and vaccine therapy.;
Looking For Signs Of Skin Cancer
Non melanoma skin cancers;tend to develop most often on skin that’s exposed to the sun.
To spot skin cancers early it helps to know how your skin normally looks. That way, you’ll notice any changes more easily.
To look at areas you cant see easily, you could try using a hand held mirror and reflect your skin onto another mirror. Or you could get your partner or a;friend to look. This is very important if you’re regularly outside in the sun for work or leisure.;
You can;take;a photo;of anything that doesn’t look quite right. If you can it’s a good idea to put a ruler or tape measure next to the abnormal area;when you take the photo. This;gives you a more accurate idea about its size and can help you tell if it’s changing. You can then show these pictures to your doctor.;
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Survival For The Ten Most Common Cancers In Females
Of the ten most common cancers in females, age-standardised ten-year net survival is highest for malignant melanoma at 92%, and lowest for pancreaticcancer at just 1%. Malignant melanoma and pancreatic cancer also have the highest and lowest ten-year survival out of all of the cancer types occurring in females, respectively. Breast, lung and bowel cancers together account for over half of all new cases in females ten-year survival for these three cancer types varies considerably, at 78%, 7% and 57%, respectively.
Age-Standardised One-, Five- and Ten-Year Survival for the 10 Most Common Cancers in Females, England and Wales, 2010-2011
Five- and ten-year survival for 2010-2011 is predicted using an excess hazard statistical model Survival for bowel cancer is a weighted average derived from data for colon and rectum cancer
Age-Standardised Ten-Year Net Survival for the Most Common Cancers in Females, England and Wales, 2010-2011
Ten-year survival for 2010-2011 is predicted using an excess hazard statistical model Survival for bowel cancer is a weighted average derived from data for colon and rectum cancer
Malignant melanoma shows one of the biggest differences in survival between the sexes, with 86% of men and 92% of women predicted to survive for ten years or more ; some of this difference may be explained by a higher proportion of thicker tumours in men, combined with other morbidity and health-related behaviours.
The 10 Deadliest Cancers And Why There’s No Cure
ByAmanda Chan10 September 2010
The dread and fear that can come with a cancer diagnosis have their roots in its killer nature: It’s the No. 2 cause of death in Americans, second only to heart disease, according to the Centers for Disease Control and Prevention. Even when diagnosed early and attacked with the latest treatments, it still has the power to kill.
To help raise money to find cures and treatments for cancer patients, the “Stand Up to Cancer” telethon will air on ABC, NBC and CBS and other networks and cable stations starting at 8 p.m. ET tonight. The telethon will feature a host of celebrity guests, including George Clooney, Denzel Washington, Renee Zellweger and Will Smith.
“‘Stand Up To Cancer’ represents collaborative efforts” to provide funding for cancer research, Dr. Len Lichtenfeld, deputy chief medical officer of the American Cancer Society, told MyHealthNewsDaily.
“We would not be where we are if basic and clinical science wasn’t funded,” Lichtenfeld said. “Basic science teaches us about mechanisms, about how drugs may be effective, and we take that info and put it into a clinic to find out whether or not those new ideas work in cancer treatment.”
Cancer cells, and how they grow, remain unpredictable and in some cases mysterious. Even after seemingly effective treatments, crafty cancer cells are able to hide out in some patients and resurface.
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What Is Most Dangerous Skin Cancer
1. Nodular melanoma
An most dangerous form of melanoma that looks various from common melanomas they are raised from the start and have an even coloring . This kind of melanoma grows really rapidly and needs to be dealt with as quickly as possible.
2. Basal cell carcinoma
This is the most typical but least dangerous kind of skin cancer. It grows slowly, generally on the head, neck and upper torso. It may look like a lump or dry, scaly area. It can be red, pale or pearly in color. As it grows, it may ulcerate or resemble a sore that does not recover correctly.
3. Squamous cell carcinoma
This type of skin cancer is not as dangerous as melanoma but may infect other parts of the body if not treated. It grows over some months and appears on skin most often exposed to the sun. It can be a thickened, red, flaky spot that may bleed quickly, crust or ulcerate.
Different Types Of Skin Cancer
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The different types of skin cancer are named after the type of skin cell they start from. There are three main types of skin cancer:
- basal cell carcinoma
- squamous cell carcinoma of the skin
- melanoma.
BCCs and SCCs are different from melanoma. They are called non-melanoma skin cancers.We have separate information about melanoma.
See also
The skin does many things. It:
- protects the body from injury and infection
- helps to control body temperature
- helps to control fluid loss
- gets rid of waste substances through the sweat glands.
The skin is divided into 2 main layers. The outer layer is the epidermis and the layer underneath is the dermis. Below these is a deeper layer of fatty tissue.
The epidermis contains several types of cells. Most of the epidermis is filled with cells called keratinocytes, also called squamous cells.
The lowest layer of the epidermis is called the basal layer. It contains rounder cells called basal cells.
The basal layer also contains skin cells called melanocytes which produce melanin. Melanin gives skin its natural colour.
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What Happens When Skin Cancer Goes Untreated
If you notice an abnormality on your skin you may be tempted to ignore it. However, if it is skin cancer you could be putting your health at risk by waiting to get a skin and mole check. There are three main types of skin cancer in Australia with melanoma, basal cell carcinoma and squamous cell carcinoma, and they each have their own set of unique characteristics. The most important thing to remember is that if you delay treatment of skin cancer it could have life threatening consequences:
What Is A Melanocyte
Melanocytes are skin cells found in the upper layer of skin. They produce a pigment known as melanin, which gives skin its color. There are two types of melanin: eumelanin and pheomelanin. When skin is exposed to ultraviolet radiation from the sun or tanning beds, it causes skin damage that triggers the melanocytes to produce more melanin, but only the eumelanin pigment attempts to protect the skin by causing the skin to darken or tan. Melanoma occurs when DNA damage from burning or tanning due to UV radiation triggers changes in the melanocytes, resulting in uncontrolled cellular growth.
About Melanin
Naturally darker-skinned people have more eumelanin and naturally fair-skinned people have more pheomelanin. While eumelanin has the ability to protect the skin from sun damage, pheomelanin does not. Thats why people with darker skin are at lower risk for developing melanoma than fair-skinned people who, due to lack of eumelanin, are more susceptible to sun damage, burning and skin cancer.
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What Causes Skin Cancer
Ultraviolet light exposure, most commonly from sunlight, is overwhelmingly the most frequent cause of skin cancer.
Other important causes of skin cancer include the following:
- Use of tanning booths
- Immunosuppression – This means impairment of the immune system. The immune system protects the body from foreign entities, such as germs or substances that cause an allergic reaction. This suppression may occur as a consequence of some diseases or can be due to medications prescribed to combat conditions such as autoimmune diseases or prevent organ transplant rejection.
- Exposure to unusually high levels of X-rays
- Contact with certain chemicals-arsenic , hydrocarbons in tar, oils, and soot
The following people are at the greatest risk:
- People with fair skin, especially types that freckle, sunburn easily, or become painful in the sun
- People with light hair and blue or green eyes
- Those with certain genetic disorders that deplete skin pigment such as albinism, xeroderma pigmentosum
- People who have already been treated for skin cancer
- People with numerous moles, unusual moles, or large moles that were present at birth
- People with close family members who have developed skin cancer
- People who had at least one severe sunburn early in life
A basal cell carcinoma usually looks like a raised, smooth, pearly bump on the sun-exposed skin of the head, neck, or shoulders.
A squamous cell carcinoma is commonly a well-defined, red, scaling, thickened patch on sun-exposed skin.
Skin Cancer Symptoms And Signs
Basal Cell Carcinoma
BCC is the most common type of skin cancer and has a predilection for sun-exposed skin. Tumors may appear as a pearly or waxy bumps usually with visible blood vessels , or as a flat scaly reddish patch with a brown border, or as a hard or scar-like lesion . Frequently BCCs can be itchy, often bleed, or in more advanced cases, ulcerate.
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Risk Of Further Melanomas
Most people treated for early melanoma do not have further trouble with the disease. However, when there is a chance that the melanoma may have spread to other parts of your body, you will need regular check-ups.;Your doctor will decide how often you will need check-ups everyone is different. They will become less frequent if you have no further problems.;After treatment for melanoma it is important to limit exposure to the sun’s UV radiation.;As biological family members usually share similar traits, your family members may also have an increased risk of developing melanoma and other skin cancers. They can reduce their risk by spending less time in the sun and using a combination of sun protection measures during sun protection times.;It is important to monitor your skin regularly and if you notice any changes in your skin, or enlarged lymph glands near to where you had the cancer, see your specialist as soon as possible.;
Squamous Cell Carcinoma Causes
Exposure to ultraviolet rays, like the ones from the sun or a tanning bed, affects the cells in the middle and outer layers of your skin and can cause them to make too many cells and not die off as they should. This can lead to out-of-control growth of these cells, which can lead to squamous cell carcinoma.
Other things can contribute to this kind of overgrowth, too, like conditions that affect your immune system.
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What Are The Risk Factors For Skin Cancer
The most common risk factors for skin cancer are as follows.
- Ultraviolet light exposure, either from the sun or from tanning beds. Fair-skinned individuals, with hazel or blue eyes, and people with blond or red hair are particularly vulnerable. The problem is worse in areas of high elevation or near the equator where sunlight exposure is more intense.
- A chronically suppressed immune system from underlying diseases such as HIV/AIDS infection or cancer, or from some medications such as prednisone or chemotherapy
- Exposure to ionizing radiation or chemicals known to predispose to cancer such as arsenic
- Certain types of sexually acquired wart virus infections
- People who have a history of one skin cancer have a 20% chance of developing second skin cancer in the next two years.
- Elderly patients have more skin cancers.
Most basal cell carcinomas have few if any symptoms. Squamous cell carcinomas may be painful. Both forms of skin cancer may appear as a sore that bleeds, oozes, crusts, or otherwise will not heal. They begin as a slowly growing bump on the skin that may bleed after minor trauma. Both kinds of skin cancers may have raised edges and central ulceration.
Signs and symptoms of basal cell carcinomas include:
Signs and symptoms of squamous cell carcinomas include:
- Persistent, scaly red patches with irregular borders that may bleed easily
- Open sore that does not go away for weeks
- A raised growth with a rough surface that is indented in the middle
- A wart-like growth