The 10 Deadliest Cancers And Why Theres No Cure
ByAmanda Chan10 September 2010
The dread and fear that can come with a cancer diagnosis have their roots in its killer nature: Its the No. 2 cause of death in Americans, second only to heart disease, according to the Centers for Disease Control and Prevention. Even when diagnosed early and attacked with the latest treatments, it still has the power to kill.
To help raise money to find cures and treatments for cancer patients, the Stand Up to Cancer telethon will air on ABC, NBC and CBS and other networks and cable stations starting at 8 p.m. ET tonight. The telethon will feature a host of celebrity guests, including George Clooney, Denzel Washington, Renee Zellweger and Will Smith.
Stand Up To Cancer represents collaborative efforts to provide funding for cancer research, Dr. Len Lichtenfeld, deputy chief medical officer of the American Cancer Society, told MyHealthNewsDaily.
We would not be where we are if basic and clinical science wasnt funded, Lichtenfeld said. Basic science teaches us about mechanisms, about how drugs may be effective, and we take that info and put it into a clinic to find out whether or not those new ideas work in cancer treatment.
Cancer cells, and how they grow, remain unpredictable and in some cases mysterious. Even after seemingly effective treatments, crafty cancer cells are able to hide out in some patients and resurface.
What Is A Melanocyte
Melanocytes are skin cells found in the upper layer of skin. They produce a pigment known as melanin, which gives skin its color. There are two types of melanin: eumelanin and pheomelanin. When skin is exposed to ultraviolet radiation from the sun or tanning beds, it causes skin damage that triggers the melanocytes to produce more melanin, but only the eumelanin pigment attempts to protect the skin by causing the skin to darken or tan. Melanoma occurs when DNA damage from burning or tanning due to UV radiation triggers changes in the melanocytes, resulting in uncontrolled cellular growth.
About Melanin
Naturally darker-skinned people have more eumelanin and naturally fair-skinned people have more pheomelanin. While eumelanin has the ability to protect the skin from sun damage, pheomelanin does not. Thats why people with darker skin are at lower risk for developing melanoma than fair-skinned people who, due to lack of eumelanin, are more susceptible to sun damage, burning and skin cancer.
Ultraviolet light exposure, most commonly from sunlight, is overwhelmingly the most frequent cause of skin cancer.
Other important causes of skin cancer include the following:
The following people are at the greatest risk:
A basal cell carcinoma usually looks like a raised, smooth, pearly bump on the sun-exposed skin of the head, neck, or shoulders.
A squamous cell carcinoma is commonly a well-defined, red, scaling, thickened patch on sun-exposed skin.
What Happens When Skin Cancer Goes Untreated
If you notice an abnormality on your skin you may be tempted to ignore it. However, if it is skin cancer you could be putting your health at risk by waiting to get a skin and mole check. There are three main types of skin cancer in Australia with melanoma, basal cell carcinoma and squamous cell carcinoma, and they each have their own set of unique characteristics. The most important thing to remember is that if you delay treatment of skin cancer it could have life threatening consequences:
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The 10 Deadliest Cancers And Why There’s No Cure
ByAmanda Chan10 September 2010
The dread and fear that can come with a cancer diagnosis have their roots in its killer nature: It’s the No. 2 cause of death in Americans, second only to heart disease, according to the Centers for Disease Control and Prevention. Even when diagnosed early and attacked with the latest treatments, it still has the power to kill.
To help raise money to find cures and treatments for cancer patients, the “Stand Up to Cancer” telethon will air on ABC, NBC and CBS and other networks and cable stations starting at 8 p.m. ET tonight. The telethon will feature a host of celebrity guests, including George Clooney, Denzel Washington, Renee Zellweger and Will Smith.
“‘Stand Up To Cancer’ represents collaborative efforts” to provide funding for cancer research, Dr. Len Lichtenfeld, deputy chief medical officer of the American Cancer Society, told MyHealthNewsDaily.
“We would not be where we are if basic and clinical science wasn’t funded,” Lichtenfeld said. “Basic science teaches us about mechanisms, about how drugs may be effective, and we take that info and put it into a clinic to find out whether or not those new ideas work in cancer treatment.”
Cancer cells, and how they grow, remain unpredictable and in some cases mysterious. Even after seemingly effective treatments, crafty cancer cells are able to hide out in some patients and resurface.
What Are The Risk Factors For Skin Cancer
The most common risk factors for skin cancer are as follows.
- Ultraviolet light exposure, either from the sun or from tanning beds. Fair-skinned individuals, with hazel or blue eyes, and people with blond or red hair are particularly vulnerable. The problem is worse in areas of high elevation or near the equator where sunlight exposure is more intense.
- A chronically suppressed immune system from underlying diseases such as HIV/AIDS infection or cancer, or from some medications such as prednisone or chemotherapy
- Exposure to ionizing radiation or chemicals known to predispose to cancer such as arsenic
- Certain types of sexually acquired wart virus infections
- People who have a history of one skin cancer have a 20% chance of developing second skin cancer in the next two years.
- Elderly patients have more skin cancers.
Most basal cell carcinomas have few if any symptoms. Squamous cell carcinomas may be painful. Both forms of skin cancer may appear as a sore that bleeds, oozes, crusts, or otherwise will not heal. They begin as a slowly growing bump on the skin that may bleed after minor trauma. Both kinds of skin cancers may have raised edges and central ulceration.
Signs and symptoms of basal cell carcinomas include:
Signs and symptoms of squamous cell carcinomas include:
- Persistent, scaly red patches with irregular borders that may bleed easily
- Open sore that does not go away for weeks
- A raised growth with a rough surface that is indented in the middle
- A wart-like growth
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What Is The Worst Organ To Have Cancer In
What is the worst organ to have cancer in ~ While prostate cancer is the most common cancer in men in the United States lung cancer again accounts for more deaths overall. Which cancer is deadliest for men. Indeed recently has been searched by consumers around us, perhaps one of you. Individuals now are accustomed to using the net in gadgets to see video and image data for inspiration, and according to the title of the post I will talk about about What Is The Worst Organ To Have Cancer In According to the National Cancer Institute each year around 119000 men are diagnosed with lung cancer.
Recurrent Basal Cell Carcinoma
Basal cell carcinomas are the most common type of skin cancer, according to the American Cancer Society. These cancers develop within the basal cell layer of the skin, in the lowest part of the epidermis.
Patients who have had basal cell carcinoma once have an increased risk of developing a recurrent basal cell cancer. Basal cell cancers may recur in the same location that the original cancer was found or elsewhere in the body. As many as 50 percent of cancer patients are estimated to experience basal cell carcinoma recurrence within five years of the first diagnosis.
Basal cell carcinomas typically grow slowly, and it is rare for them to metastasize or spread to nearby lymph nodes or other parts of the body. But early detection and treatment are important.
After completing treatment for basal cell carcinoma, it is important to perform regular self-examinations of the skin to look for new symptoms, such as unusual growths or changes in the size, shape or color of an existing spot. Skin cancers typically develop in areas of the body that are exposed to the sun, but they may also develop in areas with no sun exposure. Tell your oncologist or dermatologist about any new symptoms or suspicious changes you may have noticed.
- Have a history of eczema or dry skin
- Have been exposed to high doses of UV light
- Had original carcinomas several layers deep in the skin
- Had original carcinomas larger than 2 centimeters
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Medical Treatment For Skin Cancer
Surgical removal is the mainstay of skin cancer treatment for both basal cell and squamous cell carcinomas. For more information, see Surgery.People who cannot undergo surgery may be treated by external radiation therapy. Radiation therapy is the use of a small beam of radiation targeted at the skin lesion. The radiation kills the abnormal cells and destroys the lesion. Radiation therapy can cause irritation or burning of the surrounding normal skin. It can also cause fatigue. These side effects are temporary. In addition, topical chemotherapy creams have been FDA approved for the treatment of certain low-risk nonmelanoma skin cancers. Patients with advanced or many basal cell carcinomas are sometimes prescribed oral pills to block the growth of these cancers. Side effects include muscle spasms, hair loss, taste changes, weight loss and fatigue.
In advanced cases of melanoma, immune therapies, vaccines, or chemotherapy may be used. These treatments are typically offered as clinical trials. Clinical trials are studies of new therapies to see if they can be tolerated and work better than existing therapies.
Risk Of Further Melanomas
Most people treated for early melanoma do not have further trouble with the disease. However, when there is a chance that the melanoma may have spread to other parts of your body, you will need regular check-ups. Your doctor will decide how often you will need check-ups everyone is different. They will become less frequent if you have no further problems. After treatment for melanoma it is important to limit exposure to the suns UV radiation. As biological family members usually share similar traits, your family members may also have an increased risk of developing melanoma and other skin cancers. They can reduce their risk by spending less time in the sun and using a combination of sun protection measures during sun protection times. It is important to monitor your skin regularly and if you notice any changes in your skin, or enlarged lymph glands near to where you had the cancer, see your specialist as soon as possible.
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Melanoma Skin Cancer Mortality
- There are around 2,300 melanoma skin cancer deaths in the UK every year, that’s more than 6 every day .
- Melanoma skin cancer is the 19th most common cause of cancer death in the UK, accounting for 1% of all cancer deaths .
- In females in the UK, melanoma skin cancer is the 18th most common cause of cancer death, with around 940 deaths in 2018.
- In males in the UK, melanoma skin cancer is the 17th most common cause of cancer death, with around 1,400 deaths in 2018.
- Mortality rates for melanoma skin cancer in the UK are highest in people aged 90+ .
- Each year almost half of all melanoma skin cancer deaths in the UK are in people aged 75 and over .
- Since the early 1970s, melanoma skin cancer mortality rates have increased by around two-and-a-half times in the UK. Rates in females have increased by around three-quarters , and rates in males have more than tripled .
- Over the last decade, melanoma skin cancer mortality rates have remained stable in the UK. Rates in females have remained stable, and rates in males have increased by almost a tenth .
- Mortality rates for melanoma skin are projected to fall by 15% in the UK between 2014 and 2035, to 4 deaths per 100,000 people by 2035.
- Melanoma skin cancer deaths are less common in males living in the most deprived areas.
Leaving Squamous Cell Carcinoma Untreated
The third type of skin cancer we have to be cautious of in Australia is squamous cell carcinoma. This is potentially life threatening and is most dangerous when found on the face, lips, ears or neck. As it grows, there is the chance it may spread to the lymph nodes and internal organs, and while it isnt as fast growing as melanoma, it still requires treatment.
You may notice squamous cell carcinoma in the top layer of your skin and it will likely be red and scaly. Surgery is often used for removal, but if it has progressed significantly some reconstruction to the face may be needed. This is the second most common form of skin cancer, and can be quite painful to touch.
All skin cancer has the potential to be fatal, and regular checks and any necessary treatment is recommended. Melanoma is by far the most serious form of skin cancer, and if suspected you should seek an urgent skin check. Please contact My Skin Centre to book your appointment in the Perth region.
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What Are The Four Main Types Of Melanoma Of The Skin
Superficial spreading melanoma
What you should know: This is the most common form of melanoma.
How and where it grows: It can arise in an existing mole or appear as a new lesion. When it begins in a mole that is already on the skin, it tends to grow on the surface of the skin for some time before penetrating more deeply. While it can be found nearly anywhere on the body, it is most likely to appear on the torso in men, the legs in women and the upper back in both.
What it looks like: It may appear as a flat or slightly raised and discolored, asymmetrical patch with uneven borders. Colors include shades of tan, brown, black, red/pink, blue or white. It can also lack pigment and appear as a pink or skin-tone lesion .
Lentigo maligna
What you should know: This form of melanoma often develops in older people. When this cancer becomes invasive or spreads beyond the original site, the disease is known as lentigo maligna melanoma.
How and where it grows: This form of melanoma is similar to the superficial spreading type, growing close to the skin surface at first. The tumor typically arises on sun-damaged skin on the face, ears, arms or upper torso.
What it looks like: It may look like a flat or slightly raised, blotchy patch with uneven borders. Color is usually blue-black, but can vary from tan to brown or dark brown.
Acral lentiginous melanoma
What you should know: This is the most common form of melanoma found in people of color, including individuals of African ancestry.
When Melanoma Cant Be Cured
If your cancer has spread and it is not possible to cure it by surgery, your doctor may still recommend treatment. In this case, treatment may help to relieve symptoms, might make you feel better and may allow you to live longer.Whether or not you choose to have anti-cancer treatment, symptoms can still be controlled. For example, if you have pain, there are effective treatments for this. General practitioners, specialists and palliative care teams in hospitals all play important roles in helping people with cancer.
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A Dangerous Skin Cancer
Melanoma is a serious form of skin cancer that begins in cells known as melanocytes. While it is less common than basal cell carcinoma and squamous cell carcinoma , melanoma is more dangerous because of its ability to spread to other organs more rapidly if it is not treated at an early stage.
Learn more about melanoma types, risk factors, causes, warning signs and treatment.
Melanoma Fact
Only 20-30% of melanomas are found in existing moles.
While 70-80% arise on normal-looking skin.
Leaving Basal Cell Carcinoma Untreated
Basal cell carcinoma is a slow growing cancer, but this doesnt mean it can be ignored. This is the least dangerous form of skin cancer and rarely spreads to other internal parts of the body. While death is a rare consequence there is the potential for disfigurement. Over time basal cell carcinoma can expand and cause ulcers and damage the skin and tissues.
Any damage could be permanent and have an impact on the way you look. Depending on how long the basal cell carcinoma has been present, radiotherapy may be required. This is the most common form of skin cancer and is often found on the face. You may notice a small lump which is shiny or pearl like and this is a sign you should get checked. This type of cancer generally does not cause any pain.
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Common Signs Of Skin Cancer
One in five Americans will be diagnosed with skin cancer before they reach the age of 70. Fortunately, with treatment, skin cancer doesn’t have to prove as damaging as you might fear. With early detection, the survival rate for melanoma is 99%.
To ensure that you have the best chances of avoiding the worst outcomes, be sure to check your skin often for warning signs and early symptoms.
How Dangerous Is Skin Cancer Really
We all love the feeling of the sun on our skin and maybe even a little bit of that golden tan. But then were reminded that somebody dies every hour in the U.S. from skin cancer. Most skin cancer cases are completely avoidable. Dr. Glen Bowen from Huntsman Cancer Institute talks about why he believes skin cancer is an epidemic problem. Hell also talk about how to balance the desire to be out in the sun and the dangers of skin cancer, and why young adults are the most prone to melanoma.
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