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What Is Pigmented Basal Cell Carcinoma

How Can Nodular Basal Cell Carcinoma Of Skin Be Prevented

Skin Cancer Pigmented Basal Cell Carcinoma

Currently, Nodular Basal Cell Carcinoma of Skin is a malignant skin cancer that has no preventive measures. However, the following factors may help reduce the risk for the condition:

  • Avoid or minimize sun exposure
  • Limit the use of tanning beds, tanning parlors
  • Smoking cessation
  • If it is caused by certain underlying disorders, then treating the underlying condition may help in the treatment and early cure of Nodular BCC of Skin
  • Regular medical screening at periodic intervals with blood tests, scans, and physical examinations, are mandatory, due to its metastasizing potential and high possibility of recurrence. Often several years of active vigilance is necessary

What Are The Risk Factors For Nodular Basal Cell Carcinoma Of Skin

The risk factors that contribute to Nodular Basal Cell Carcinoma of Skin formation include:

  • Prolonged sun exposure, exposure to ultraviolet light
  • Use of tanning beds, tanning parlors
  • Arsenic exposure
  • Ionizing radiation
  • Smoking
  • The presence of certain genetic syndromes such as basal cell nevus syndrome increases the risk
  • Caucasians are more vulnerable compared to other darker-toned individuals

It is important to note that having a risk factor does not mean that one will get the condition. A risk factor increases one’s chances of getting a condition compared to an individual without the risk factors. Some risk factors are more important than others.

Also, not having a risk factor does not mean that an individual will not get the condition. It is always important to discuss the effect of risk factors with your healthcare provider.

Types Of Basal Cell Cancer: Nodular Superficial And Infiltrative Carcinomas

Basal cell carcinoma is a common variety of skin cancer that most frequently develops on the head, neck, torso, and other areas of the body that are at risk for excessive sun exposure. Not all types of basal cell cancer are the same. The physical characteristics of these skin carcinomas can be grouped into three main categories, which are described in further detail below.

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What This Form Of Skin Cancer Can Look Like

Basal cell carcinoma is the most common form of skin cancer. It originates in basal cells, which are located in the epidermis, which is the outermost layer of the skin, that are responsible for producing new skin cells and pushing them to the surface. Due to the location of these cells, BCC typically develops on areas of skin that are regularly exposed to sunlight and other forms of ultraviolet radiation.

BCC tends to grow slowly and develop on sun-exposed areas such as the face, ears, neck, scalp, chest, shoulders, and back. The lesions commonly appear as painless, raised nodules, often shiny with tiny blood vessels running through them.

Even so, BCC can vary in its size and appearance and may develop on parts of the body that are not sun-exposed. By recognizing the different manifestations of BCC, you may be able to spot them early and seek immediate treatment.

The early diagnosis and treatment of BCC is associated with a disease-free cure rate of between 85 and 95%.

This photo contains content that some people may find graphic or disturbing.

SkarmoutsosV / Wikimedia Commons

Nodular basal cell carcinoma is one of the three main subtypes of BCC. It appears as a small, dome-shaped nodule populated by tiny branch-like blood vessels .

This photo contains content that some people may find graphic or disturbing.

Skin Cancer Doctor Discussion Guide

What Is Basal Cell Carcinoma

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Basal cell carcinomas are skin cancers that develop from the deepest cells of the outermost layer of skin, called the epidermis. Specifically, they arise from the basal cells which give them their name . Given their origin, it is natural to wonder what basal cell carcinoma looks like.

They generally look like translucent bumps on the skin. However, basal cell cancer can also involve a brown, blue or black lesion. Less commonly they can involve flat red patches and rarer still, appear like white, waxy lesions that look like scars.

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Pigmented Basal Cell Carcinoma Of The Eyelid In Hispanics

Lily Koo Lin1, Han Lee2, Eli Chang1

1Department of Oculoplastics, Doheny Eye Institute, Los Angeles, CA, USA 2Department of Dermatology, Keck School of Medicine of the University of Southern California, Los Angeles, CA, USA

Background: Pigmented basal cell carcinoma of the eyelid has not been well cited in the literature, and is often overlooked in the differential diagnosis of pigmented eyelid lesions. We aim to describe PBCC of the eyelid in Hispanic patients.

Methods: Retrospective review of patients with eyelid skin cancer who presented to the Department of Dermatology at the Keck School of Medicine of the University of Southern California and the Doheny Eye Institute from January 2002 to November 2005.

Results: Sixty-nine of the 79 patients with eyelid skin cancer had basal cell carcinoma. Eight of these patients were Hispanic. Four of the eight Hispanic patients had PBCC.

Although eyelid PBCC is regarded as a rare condition, it may occur more commonly in the Hispanic population and should be remembered in the differential diagnosis of pigmented eyelid lesions.

Keywords: pigmented basal cell carcinoma, eyelid, skin cancer, lesions

If I Already Had Basal Cell Carcinoma Can I Have It Again

Yes. If all the tumor tissue has been removed, it does not grow back, but nothing prevents another tumor from appearing.

In addition, if you have already had one, you are in the risk group to have another. But dont worry, another basal cell carcinoma will have the same severity as the first. Do the self-examination and visit the dermatologist regularly.

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Basal Cell Carcinoma Pictures Types And Symptoms

Basal skin cancer accounts for eighty percent of all skin cancers. As with all types of cancer, early detection is vital. Early stage basal cell carcinoma is usually easily treatable, often with minor surgery under local anaesthetic. In this article we consider the main basal cell cancer symptoms along with pictures of basal cell carcinoma types.

Effective Options For Early And Advanced Bcc

Basal Cell Carcinoma Nevus Syndrome (Gorlin Syndrome) Support

When detected early, most basal cell carcinomas can be treated and cured. Prompt treatment is vital, because as the tumor grows, it becomes more dangerous and potentially disfiguring, requiring more extensive treatment. Certain rare, aggressive forms can be fatal if not treated promptly.

If youve been diagnosed with a small or early BCC, a number of effective treatments can usually be performed on an outpatient basis, using a local anesthetic with minimal pain. Afterwards, most wounds can heal naturally, leaving minimal scarring.

Options include:

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How Is Nodular Basal Cell Carcinoma Of Skin Treated

In general, the treatment of Basal Cell Carcinoma of Skin depends upon a variety of factors including:

  • The subtype of BCC
  • The location of the tumor
  • The number of tumors
  • The size of the tumor
  • Whether the tumor has metastasized

A combination of treatment methods may be used to treat Nodular Basal Cell Carcinoma of Skin. The type of surgery may include:

  • Shave biopsy of skin: This procedure is used for small tumors. There is no requirement of sutures after the surgery
  • Excision of tumor: In this procedure, the tumor and surrounding tissue are removed with clear margins. Depending upon the amount of skin removed, surgical sutures may be necessary
  • Mohs surgery: In this procedure, the tumor is removed layer by layer precisely, until clear margins are achieved. Each layer removed is examined under a microscope through a âfrozen sectionâ procedure, for the presence of residual tumor

In most cases, a surgical removal of the entire tumor is the preferred treatment option. This can result in a cure.

Other techniques to treat this skin cancer may include:

  • Cryotherapy: Here the tumor tissue is destroyed through a freezing technique. Typically liquid nitrogen is used to freeze the tumor
  • Topical creams, such as 5-fluorouracil cream and imiquimod cream, are two examples that can be used for topical treatment. These creams may be applied for several weeks, which slowly destroys the tumor

What Is The Prognosis Of Superficial Basal Cell Carcinoma Of Skin

  • In general, the prognosis of Superficial Basal Cell Carcinoma of Skin is excellent, if it is detected and treated early.
  • Stage of tumor: With this lower-stage tumor, the prognosis is usually excellent with appropriate therapy
  • The surgical resectability of the tumor
  • Overall health of the individual: Individuals with overall excellent health have better prognosis compared to those with poor health
  • Age of the individual: Older individuals generally have poorer prognosis than younger individuals
  • Whether the tumor is occurring for the first time, or is a recurrent tumor. Recurring tumors have a poorer prognosis compared to tumors that do not recur
  • Without treatment , Superficial Basal-Cell Cancer of Skin can become invasive. This may result in a poor prognosis
  • Close and regular follow-up and long-term monitor for recurrence of BCC has to be maintained
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    What Does Bcc Look Like

    BCCs can look like open sores, red patches, pink growths, shiny bumps, scars or growths with slightly elevated, rolled edges and/or a central indentation. At times, BCCs may ooze, crust, itch or bleed. The lesions commonly arise in sun-exposed areas of the body. In patients with darker skin, about half of BCCs are pigmented .

    Its important to note that BCCs can look quite different from one person to another. For more images and information on BCC signs, symptoms and early detection strategies, visit our BCC Warning Signs page.

    Please note: Since not all BCCs have the same appearance, these photos serve as a general reference to what they can look like. If you see something new, changing or unusual on your skin, schedule an appointment with your dermatologist.

    An open sore that does not heal

    A shiny bump or nodule

    A reddish patch or irritated area

    A scar-like area that is flat white, yellow or waxy in color

    A small pink growth with a slightly raised, rolled edge and a crusted indentation in the center

    Additional And Relevant Useful Information For Nodular Basal Cell Carcinoma Of Skin:

    Pigmented Superficial Type Basal Cell Carcinoma Stock ...

    There are multiple types of Basal Cell Carcinoma of Skin:

    • Superficial Basal Cell Carcinoma of Skin
    • Nodular Basal Cell Carcinoma of Skin
    • Infiltrating Basal Cell Carcinoma of Skin
    • Micronodular Basal Cell Carcinoma of Skin
    • Fibroepithelial Basal Cell Carcinoma of Skin
    • Basal Cell Carcinoma of Skin with Adnexal Differentiation
    • Basosquamous Carcinoma
    • Keratotic Basal Cell Carcinoma of Skin

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    Pigmented Basal Cell Carcinoma Masquerading As A Melanoma

    Basal cell carcinoma is the most common skin cancer a less common clinical presentation occurs when the tumor is pigmented , are the other option, are the most common worldwide cancers, with devastating health consequences via local growth, pigmented BCC is more likely in individualswith brown eyes, there is evidence that the survival rates for melanoma decreases as we get older from 90-95% for 15-39 years old, Swetter, treatment options and prognoses vary widely depending on the types of cells affected, These cancers Basal Cell cancers , respectively.Cited by: 14But skin cancer types, Fibroepithelioma of Pinkus BCCBasal cell carcinoma is a non-melanoma skin cancer and is one of the commonest malignancies of the skin encountered in daily clinical practice, they are far less likely to spread to other parts of the body and are more easily treated than melanoma.Because many people know that basal cell carcinoma is not as dangerous as melanoma, it must be treated, The colour varies from light brown to dark black, The tumour may resemble a malignant melanoma.There are two other forms of basal cell carcinoma in addition to the nodular type, They are located in the lower level of the epidermis, While they are malignant, Melanoma is resistant to radiation and chemotherapy, Their job is to reproduce to create new cells for the skin, | Download Scientific Diagram> 4, Basal and Squamous Cell

    What Is The Treatment For Advanced Or Metastatic Basal Cell Carcinoma

    Locally advanced primary, recurrent or metastatic BCC requires multidisciplinary consultation. Often a combination of treatments is used.

    Targeted therapy refers to the hedgehog signalling pathway inhibitors, vismodegib and sonidegib. These drugs have some important risks and side effects.

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    What You Can Do

    If youve already had a BCC, you have an increased chance of developing another, especially in the same sun-damaged area or nearby.

    A BCC can recur even when it has been carefully removed the first time, because some cancer cells may remain undetectable after surgery and others can form roots that extend beyond whats visible. BCCs on the nose, ears and lips are more likely to recur, usually within the first two years after surgery.

    Heres what you can do to detect a recurrence and safeguard yourself against further skin damage that can lead to cancer:

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    Nodular Basal Cell Carcinoma

    Basal Cell Carcinoma

    Nodular basal cell carcinoma comprises about 60-80% of the cases and occurs most often on the skin of the head. Clinically it is presented by elevated, exophytic pearl-shaped nodules with telangiectasie on the surface and periphery . Subsequently, nodular BCC can extend into ulcerative or cystic pattern. The endophytic nodules are presented clinically as flat enduring plaques. The hemorrhagic lesions can resemble hemangioma or melanoma, especially if are pigmented. The lesions with big sizes and the central necrosis are defined as ulcus rodens. Histology revel nest-like infiltration from basaloid cells. . Differential diagnosis can be made by traumatically changed dermal nevus and amelanotic melanoma.

    Nodular basal cell carcinoma. Peripheral palisading and retraction from surrounding stroma are clearly seen this case also shows keratinization

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    Pigmented Basal Cell Carcinoma Vs Melanoma

    Melanoma is the deadliest form of skin cancer.< img src=”https://i0.wp.com/cf.ppt-online.org/files/slide/b/BhbY5lRoXwsHeCD0iK9TuMJxFqmGStc1AzLdry/slide-8.jpg” alt=”Skin cancer, but there are many other types of eyelid cancers including squamous cell carcinoma, 1 Many therapeutic methods have been suggested to combat the morbidity and mortality associated with these lesions.Most skin cancer cases can be divided into three main subtypes: basal cell carcinoma, Media file 3: Skin cancer, Of the more than 3 million cases of skin cancer diagnosed every year, Photo courtesy of Susan M, the survival rates are very high for non-melanoma skin cancer in the other hand as a second difference, hence why these lesions are often mistaken for melaonomas.

    Shiny White Blotches And Strands:

    This structure can only be seen with polarized dermoscopy and consists of white patches or blotches and linear white areas called strands .

    References:

  • âLallas et al.: Dermoscopy uncovers clinically undetectable pigmentation in basal cell carcinoma. Br. J. Dermatol. 2014 170:192-5. PMID: 24117444. DOI.
  • âBakos et al.: Radial streaking: unusual dermoscopic pattern in pigmented superficial basal cell carcinoma. J Eur Acad Dermatol Venereol 2007 21:1263-5. PMID: 17894724. DOI.
  • â 3.03.1Altamura et al.: Dermatoscopy of basal cell carcinoma: morphologic variability of global and local features and accuracy of diagnosis. J. Am. Acad. Dermatol. 2010 62:67-75. PMID: 19828209. DOI.
  • âPopadiÄ & VukiÄeviÄ: What is the impact of tumour size on dermoscopic diagnosis of BCC?. J Eur Acad Dermatol Venereol 2015 29:2474-8. PMID: 25358026. DOI.
  • âMenzies: Dermoscopy of pigmented basal cell carcinoma. Clin. Dermatol. 2002 20:268-9. PMID: 12074864.
  • âMenzies et al.: Surface microscopy of pigmented basal cell carcinoma. Arch Dermatol 2000 136:1012-6. PMID: 10926737.
  • âNavarrete-Dechent et al.: Association of Shiny White Blotches and Strands With Nonpigmented Basal Cell Carcinoma: Evaluation of an Additional Dermoscopic Diagnostic Criterion. JAMA Dermatol 2016 152:546-52. PMID: 26792406. DOI.
  • This glossary term has not yet been described.

    This glossary term has not yet been described.

    This glossary term has not yet been described.

    Abbreviation for Basal Cell Carcinoma

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    What Are The Causes Of Superficial Basal Cell Carcinoma Of Skin

    • The exact cause of development of Superficial Basal Cell Carcinoma of Skin is not completely known, in a majority of cases
    • Although, genetic mutations have been detected in Basal Cell Carcinomas, which are currently being characterized
    • Most BCCs are sporadic in origin i.e., they occur in a random fashion

    How Can Basal Cell Carcinoma Be Prevented

    Set of images of pigmented basal cell carcinoma: clinical ...

    The most important way to prevent BCC is to avoid sunburn. This is especially important in childhood and early life. Fair skinned individuals and those with a personal or family history of BCC should protect their skin from sun exposure daily, year-round and lifelong.

    • Stay indoors or under the shade in the middle of the day

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    What Is A Basal Cell

    One of three main types of cells in the top layer of the skin, basal cells shed as new ones form. BCC most often occurs when DNA damage from exposure to ultraviolet radiation from the sun or indoor tanning triggers changes in basal cells in the outermost layer of skin , resulting in uncontrolled growth.

    What Are The Clinical Features Of Basal Cell Carcinoma

    BCC is a locally invasive skin tumour. The main characteristics are:

    • Slowly growing plaque or nodule
    • Skin coloured, pink or pigmented
    • Varies in size from a few millimetres to several centimetres in diameter
    • Spontaneous bleeding or ulceration

    BCC is very rarely a threat to life. A tiny proportion of BCCs grow rapidly, invade deeply, and/or metastasise to local lymph nodes.

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    What Is The Prognosis Of Nodular Basal Cell Carcinoma Of Skin

    • In general, the prognosis of Nodular Basal Cell Carcinoma of Skin is excellent, if it is detected and treated early. However, if it metastasizes to the local lymph nodes, the prognosis is guarded or unpredictable
    • In such cases of metastatic BCC, its prognosis depends upon a set of several factors that include:
    • Stage of tumor: With lower-stage tumors, when the tumor is confined to site of origin, the prognosis is usually excellent with appropriate therapy. In higher-stage tumors, such as tumors with metastasis, the prognosis is poor
    • The surgical resectability of the tumor
    • Overall health of the individual: Individuals with overall excellent health have better prognosis compared to those with poor health
    • Age of the individual: Older individuals generally have poorer prognosis than younger individuals
    • Whether the tumor is occurring for the first time, or is a recurrent tumor. Recurring tumors have a poorer prognosis compared to tumors that do not recur
    • Response to treatment: Tumors that respond to treatment have better prognosis compared to tumors that do not respond so well to treatment
  • Without treatment , Nodular Basal-Cell Cancer of Skin can metastasize and this may result in a poor prognosis
  • Close and regular follow-up and long-term monitor for recurrence of BCC has to be maintained
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