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What Does Hepatocellular Carcinoma Mean

How Is Hepatocellular Carcinoma Treated

What Does a Person with (Undiagnosed) Hepatocellular Carcinoma Look Like?

There are several ways to treat hepatocellular carcinoma. Your healthcare providers will develop a treatment plan that takes into account your overall health, whether your liver is working well and your tumors size.

Beyond that, theyll talk to you about treatment goals, options and potential side effects. They want you to have a complete picture of your situation so you can feel confident about your decisions. Once theyve shared information, theyll ask about your personal preferences. Your final treatment plan will reflect your providers recommendations and your preferences.

Treatment For Hepatocellular Carcinoma

Hepatocellular carcinoma treatment is guided by several factors including the size of the tumor, number of tumors, location of tumor, overall liver function and other health factors. Every person is different and so too is each diagnosis of liver cancer. Working with their treatment team to make a personalized plan based on the cancer stage is important for every patient.

Choosing a doctor and healthcare team is an important and very personal decision. The chosen treatment plan may mean that the doctor that diagnosed the liver cancer is not the one doing the majority of the treatment. Consider working with a multidisciplinary team if possible. A multidisciplinary team is a group of health care professionals from different specialties working together to suggest a treatment and care plan based on your diagnosis, personal health, and preferences.

Physicians involved in liver cancer care may include

  • Hepatologist

  • Financial coordinator

  • Psychologist

Each treatment is different and most treatments have some side effects that affect people differently. It is important to remember that while people may have some side effects from treatment, most people do not experience all of the potential side effects. Talk often and openly about what to expect for treatment and plan to manage side effects before and when they happen.

Can Hcc Cancer Be Cured

Whatever the underlying disease, it takes many years of continual liver damage before HCC develops in most cases cirrhosis, a hardening of the liver due to built-up scar tissue, is already present. HCC usually grows slowly in its early stages as a result HCC can usually be cured if discovered early enough.

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Taking Care Of Yourself

While you’re getting treatment, there are lots of things you can do to manage side effects and stay healthy.

Since chemotherapy can sometimes upset your stomach, you can try changing some of your eating habits. For instance, stay away from fried or spicy foods. You can also try eating five or six small meals a day rather than the traditional three meals.

If your treatment makes you tired, you can try to take short naps. You also might find that short walks can help boost your energy.

If you’re stressed about your treatment, sometimes deep breathing and meditation might help you relax.

Reach out to family and friends who can give you emotional support when you need it.

What Causes Hepatocellular Carcinoma

Cirrhosis

Cirrhosis of the liver is the most common cause of hepatocellular carcinoma. Increasingly, healthcare providers are seeing hepatocellular carcinoma cases in people who have non-alcoholic fatty liver disease . There are other medical conditions and activities that increase your risk of developing hepatocellular carcinoma.

  • Kidney function .

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Living With Advanced Cancer

Advanced cancer usually means cancer that is unlikely to be cured. Some people can live for many months or years with advanced cancer. During this time palliative care services can help.

Most people continue to have treatment for advanced cancer as part of palliative care, as it helps manage the cancer and improve their day-to-day lives. Many people think that palliative care is for people who are dying, but palliative care is for any stage of advanced cancer. There are doctors, nurses and others who specialise in palliative care.

Treatment may include chemotherapy, radiation therapy, or another type of treatment. It can help in these ways:

  • slow the growth of the cancer
  • shrink the cancer
  • help you to live more comfortably by managing symptoms, like pain.

Treatment depends on:

  • how far it has spread
  • your general health

Does Hepatocellular Disease Mean Cancer

4.3/5Hepatocellular carcinomaisliver cancerHepatocellular carcinomaliver diseases

Similarly, you may ask, what does hepatocellular disease mean?

Hepatocellular carcinoma: A cancer arising from the liver cells . Cirrhosis may be caused by viral hepatitis, primarily hepatitis B and C, alcohol abuse, hemochromatosis, certain autoimmune diseases of the liver, and other diseases that result in chronic inflammation of the liver.

Furthermore, is hepatocellular carcinoma benign or malignant? A hemangioma is a non-cancerous tumor that consists of an overgrowth of blood vessels. Another benign tumor that can occur in the liver is focal nodular hyperplasia. A liver hemangioma and focal nodular hyperplasia are the two most common tumors of the liver.

Thereof, is hepatocellular disease always cancer?

The most common form of liver cancer begins in cells called hepatocytes and is called hepatocellular carcinoma. Liver cancer is cancer that begins in the cells of your liver. The most common type of liver cancer is hepatocellular carcinoma, which begins in the main type of liver cell .

Is hepatocellular carcinoma curable?

Hepatocellular carcinoma is a cancer that starts in your liver. It’s different from “secondary” liver cancers, which have spread to the liver from other organs. If caught early, it can sometimes be cured with surgery or transplant. Surgery, radiation, and chemotherapy are some of your choices.

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What Is Hepatocellular Carcinoma

Hepatocellular carcinoma is the most common form of liver cancer. It is a serious illness that can be life-threatening. If it diagnosed early, hepatocellular carcinoma can be treated with surgery to remove the cancerous tumor or with a liver transplant. Other treatments can shrink the tumor or slow its growth and relieve your symptoms. Hepatocellular carcinoma is linked to cirrhosis of the liver and non-alcoholic fatty liver disease . People who have cirrhosis or NAFLD should be regularly checked for signs of hepatocellular carcinoma.

Risk Factors For Liver Cancer

Hepatocellular Carcinoma Lecture Simplified

There are some things that can make you more likely to develop primary liver cancer. These are called risk factors and they include long-term infection with the hepatitis B or C virus, smoking and liver scarring, known as cirrhosis.

Cirrhosis may develop slowly over months or years. These are some of the things that can cause cirrhosis:

  • hepatitis B or C
  • alcohol consumption
  • type 2 diabetes
  • genetic disorders such as iron overload or low levels of a particular protein that can cause tissue in the lungs and liver to break down .

Having these risk factors doesnt mean you will develop primary liver cancer. Sometimes there is no clear reason for getting primary liver cancer. If you are worried about your risk factors, ask your doctor for advice.

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Types Of Liver Cancer

The main type of primary liver cancer that can affect adults is hepatocellular carcinoma . HCC starts in the hepatocytes, the main type of cell in the liver, and is also known as hepatoma.

HCC is the most common type of primary liver cancer, but there are other less common types:

  • cholangiocarcinoma, also known as bile duct cancer, can start in the bile ducts that connect the liver to the bowel and gall bladder
  • angiosarcoma is a very rare type of liver cancer that starts in the blood vessels
  • hepatoblastoma is a form of liver cancer that affects only young children and is also very rare.

Side Effects Of Treatment For Liver Cancer

All cancer treatments can have side effects. Your treatment team will discuss these with you before you start treatment. Talk to your doctor or nurse about any side effects you are experiencing. Some side effects can be upsetting and difficult, but there is help if you need it. Call or email to speak with a caring cancer nurse for support.

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Signs And Symptoms Of Liver Cancer

Liver cancer often doesnt cause any symptoms in the early stages, but they may appear as the cancer grows or spreads. There are several possible symptoms:

  • weakness and tiredness
  • a swollen abdomen caused by fluid build-up
  • fever.

Not everyone with these symptoms has liver cancer. If you have any of these symptoms or are worried, always see your doctor.

What Are Other Treatments For Hepatocellular Carcinoma

The role of JNK in the development of hepatocellular carcinoma

Other treatments are:

  • Ablation therapy. Your healthcare provider uses a special needle to burn your tumors.
  • Embolization therapy or chemoembolization therapy. Healthcare providers inject chemotherapy drugs into your livers main artery, which carries the drugs to your tumor. Then they temporarily block your artery so the drugs stay in your tumor longer.
  • Targeted therapy. This treatment blocks the growth of cancer cells and limits damage to healthy cells by targeting the cancer cells genes.

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Prognosis Of Hepatocellular Carcinoma

Most people with hepatocellular carcinoma do not live for more than a few years because the cancer is detected at a late stage. Screening and early detection result in a better prognosis. If the cancer is small and has not spread and liver transplantation Liver Transplantation Liver transplantation is the surgical removal of a healthy liver or sometimes a part of a liver from a living person and then its transfer into a person whose liver no longer functions. (See… read more can be done, the person can often live a number of years.

How Does Hepatocellular Carcinoma Affect My Body

Over time, hepatocellular carcinoma can cause liver failure. Before that happens, however, hepatocellular carcinoma can keep your liver from managing your bodys vital functions. Among other things, your liver:

  • Keeps track of your bodys nutrients, converting them into substances your body can use, storing and delivering them to your cells as needed.
  • Gathers toxic substances, making sure they are harmless or released from your body.
  • Supports healthy blood flow, producing substances that help your blood to clot and removing bacteria that cause infection.

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Measurement Of Tumor Volume Doubling Time

This study included 3-phase and 4-phase contrast-enhanced dynamic CT and MRI studies. When more than two imaging studies were available, we selected two for TVDT calculation according to the following principles. First, two studies with the same imaging modality were chosen whenever possible. Second, if a patient had multiple follow-up examinations with the same imaging modality, only the follow-up with the maximum interval was used. Third, MRI was preferred over CT. The interval between the initial and last imaging studies ranged from 30 to 777 days .

Two radiologists who were unaware of the patients’ clinical information measured the size of each HCC using the best available image of the tumor, with preference given to delayed images followed by portal phase images and finally arterial phase images. The average tumor diameter was calculated from the two greatest perpendicular dimensions, as measured on transverse images. The tumor size was then used to determine the tumor volume calculated as TV = ×× 3, where D is the average diameter. On follow-up imaging, the same plane of section was used to measure the tumor size and volume. The growth rate of the HCC was expressed as TVDT calculated using Schwartz’s equation: TVDT = × log2 / , where indicates the time interval between two measurements, and V0 and V represent the tumor volumes at the two measurement times. Based on the calculated TVDT, the time needed for each 1 cm increase in tumor diameter was also calculated.

Prevention Of Hepatocellular Carcinoma

Hepatocellular Carcinoma: Treating Liver Cancer
  • Selective internal radiation therapy

However, these treatments do not destroy all the cancer cells.

Chemotherapy drugs can be injected into a blood vessel that supplies a tumor . For example, drugs can be injected into a vein or into the hepatic artery. Injecting chemotherapy drugs directly into the hepatic artery delivers a large amount of the drugs directly to the cancer cells in the liver. The chemotherapy drug sorafenib is effective against hepatocellular carcinoma. Other chemotherapy drugs and immunotherapy drugs are now being used in some people with this cancer.

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North America And Western Europe

The most common malignant tumors in the liver represent metastases from tumors which originate elsewhere in the body. Among cancers that originate from liver tissue, HCC is the most common primary liver cancer. In the United States, the US surveillance, epidemiology, and end results database program, shows that HCC accounts for 65% of all cases of liver cancers. As screening programs are in place for high-risk persons with chronic liver disease, HCC is often discovered much earlier in Western countries than in developing regions such as sub-Saharan Africa.

Acute and chronic hepatic porphyrias and tyrosinemia type I are risk factors for hepatocellular carcinoma. The diagnosis of an acute hepatic porphyria should be sought in patients with HCC without typical risk factors of hepatitis B or C, alcoholic liver cirrhosis, or hemochromatosis. Both active and latent genetic carriers of acute hepatic porphyriasare at risk for this cancer, although latent genetic carriers have developed the cancer at a later age than those with classic symptoms. Patients with acute hepatic porphyrias should be monitored for HCC.

The incidence of HCC is relatively lower in the Western Hemisphere than in Eastern Asia. However, despite the statistics being low, the diagnosis of HCC has increased since the 1980s and it is continuing to increase, making it one of the rising causes of death due to cancer. The common risk factor for HCC is hepatitis C, along with other health issues.

Examples Of Hepatocellular In A Sentence

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These example sentences are selected automatically from various online news sources to reflect current usage of the word ‘hepatocellular.’ Views expressed in the examples do not represent the opinion of Merriam-Webster or its editors. Send us feedback.

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How Can I Reduce The Risk Ill Develop Hepatocellular Carcinoma

Fortunately, there are several ways you can reduce your risk of developing hepatocellular carcinoma:

  • Get your hepatitis B vaccination. There isnt a vaccine for hepatitis C.
  • Talk to your healthcare provider if you think you might have hepatitis B and hepatitis C.
  • Cut back on the amount of alcohol you drink.
  • Maintain a healthy weight.

Clinical Patterns Of Hepatocellular Carcinoma In Nonalcoholic Fatty Liver Disease: A Multicenter Prospective Study

HCC

Centro Studi Fegato, Fondazione Italiana Fegato-Science Park-Basovizza Campus, Trieste, Italy

Dipartimento di Scienze Mediche, Università di Trieste, Trieste, Italy

Corresponding Author

Centro Studi Fegato, Fondazione Italiana Fegato-Science Park-Basovizza Campus, Trieste, Italy

The names and affiliations of all members of the HCC-NAFLD Italian Study Group are listed as an appendix.

Centro Studi Fegato, Fondazione Italiana Fegato-Science Park-Basovizza Campus, Trieste, Italy

Dipartimento di Scienze Mediche, Università di Trieste, Trieste, Italy

Corresponding Author

Centro Studi Fegato, Fondazione Italiana Fegato-Science Park-Basovizza Campus, Trieste, Italy

The names and affiliations of all members of the HCC-NAFLD Italian Study Group are listed as an appendix.

Potential conflict of interest: Nothing to report.

Supported by the European Union Seventh Framework Program under grant agreement Health-F2-2009-241762, for the FLIP program, and by an internal research grant from the Italian Liver Foundation.

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Symptoms Of Hepatocellular Carcinoma

Usually, the first symptoms are abdominal pain, weight loss, and a large mass that can be felt in the upper right part of the abdomen. People who have had cirrhosis Cirrhosis of the Liver Cirrhosis is the widespread distortion of the liver’s internal structure that occurs when a large amount of normal liver tissue is permanently replaced with nonfunctioning scar tissue. The scar… read more for a long time may unexpectedly become much more ill. A fever may occur. Occasionally, the first symptoms are sudden abdominal pain and shock caused by rupture or bleeding of the cancer.

Stages Of Liver Cancer

The stage of a cancer describes its size and whether it has spread from where it first started.

Knowing the stage helps you and your doctors to decide on the best treatment for you. For liver cancer, doctors also use the Child-Pugh score when planning treatment. This looks at how well the liver is working.

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Treatment For Liver Cancer

Treatment for liver cancer will depend on whether it is a primary or secondary cancer. Treatment also depends on the size of the cancer, whether it is contained in one part of the liver, whether major blood vessels are involved and whether you have cirrhosis. Your doctor will also consider your age, your general health and the options available at your hospital.

You might feel confused or unsure about your treatment options and decisions. Its okay to ask your treatment team to explain the information to you more than once. Its often okay to take some time to think about your decisions.

Prognosis And Survival Rates For Liver Cancer

Hepatocellular Carcinoma

When someone is diagnosed with liver cancer, their doctor will give them a prognosis. A prognosis is the doctors opinion of how likely it is that the cancer will spread, and the chances of getting better. A prognosis depends on the type and stage of cancer, as well as the persons age and general health.

If you have liver cancer, your doctor will talk to you about your individual situation when working out your prognosis. Every persons experience is different and there is support available to you.

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Hepatocellular Diseases Of The Liver

There are many types of hepatocellular diseases ranging from infections and cancers. The liver is one of the biggest organs in the body and is located just underneath the right rib cage. The liver is also the powerhouse/engine of the body and plays a vital role in many functions like metabolism and breakdown of many substances. Without the liver, survival would be impossible.

What is hepatocellular disease?

The liver can be affected by infections, drugs or toxic chemicals. The majority of liver problems are transient or acute in nature because the liver has great healing power. However, chronic hepatocellular disease can last for a long time and present with a variety of symptoms. The classic symptoms of diffuse hepatocellular liver disease include:

⢠Yellowish discoloration of the skin and eyes⢠Abdominal pain⢠Distension of the abdomen⢠Severe itching of skin⢠Dark or tea colored urine⢠Pale stools⢠Intermittent blood in the stools⢠Extreme fatigue

Intravenous drug use and sharing needles Exposure to toxic chemicals Having unprotected sex

Diagnosis of hepatocellular disorders includes:

The treatment of diffuse hepatocellular disease depends on the cause. While most cases can be treated with medications, some liver disorders may require surgery. If the liver is failing, the other option may be a liver transplant.

The best way to avoid liver disease is by preventing the problem in the first place. This means:

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