What Are The Types Of Squamous Cell Carcinoma
Squamous cell carcinoma develops when the flat cells in the toplayer of skin grow and divide in an uncontrolled way.
You can get an SCC wherever there are squamous cells which is in manydifferent parts of the body. However, typically they appear on parts of theskin that have been exposed to a lot of ultraviolet radiation from the sunor from tanning beds.
An early form of skin cancer, called Bowen’s disease, which looks like a red, scaly patch, can also develop into an SCC if nottreated.
An SCC can be quite an aggressive cancer if left untreated. If you evernotice a sore, scab or scaly patch of skin that doesnt heal within 2 months,see a doctor.
Possible Causes Of Burning Sensation On The Skin
When there is tissue damage or any risk of injury to the skin, it is perceived in various different types of sensations. It can be perceived either as pain, itching or skin feels like it’s burning. The sensations are indications for us to take action against the agent which is causing the harm. There can be situations where in the sensations in the skin occur without any underlying cause or reason. Burning can be caused due to an injury, allergy, drug reaction, nerve disorder, poisoning or disease.
What Causes Basal Cell Carcinoma
The commonest cause is exposure to ultraviolet light from the sun or from sunbeds. BCCs can occur anywhere on the body, but are most common on areas that are exposed to the sun such as your face, head, neck and ears. It is also possible for a BCC to develop in a longstanding scar. BCCs are not infectious.
BCCs mainly affect fair skinned adults, but other skin types are also at risk. Those with the highest risk of developing a basal cell carcinoma are:
- People with pale skin who burn easily and rarely tan .
- Those who have had a lot of exposure to the sun, such as people with outdoor hobbies or outdoor workers, and people who have lived in sunny climates.
- People who have used sun beds or have regularly sunbathed.
- People who have previously had a basal cell carcinoma.
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What Is Skin Cancer And Melanoma
Skin cancer is a disease that occurs when your skin cells grow abnormally, usually from too much exposure to ultraviolet radiation from the sun.
This uncontrolled growth of abnormal cells forms a tumour in the skin. Tumours are either benign , or malignant .
Skin cancer is the most common type of cancer: each year, more than 13,000 Australians are diagnosed with a melanoma and almost 980,000 new cases of non-melanoma skin cancers are treated. Skin cancer is mostly preventable, and there are effective treatment options available.
Skin cancers are named according to the cells in which they form. There are 3 main types:
- Basal cell carcinoma begins in the lower segment of cells of the epidermis your outer layer of skin. These tend to grow slowly, and rarely spread to other parts of the body.
- Squamous cell carcinoma grows from the flat cells found in the top layer of your epidermis. SCC can grow quickly on the skin over several weeks or months. Bowens disease is an early form of SCC that hasnt grown beyond the top layer of skin.
- Melanoma grows from cells called melanocytes cells that give your skin its colour. Melanoma is the rarest type of skin cancer but is considered the most serious because it can spread quickly throughout the body.
BCC and SCC are also called non-melanoma skin cancers. BCC represents more than 2 in 3 non-melanoma skin cancers, and around 1 in 3 are SCC. There are other types of non-melanoma skin cancers, but they are rare.
Melanoma Signs And Symptoms

Melanoma skin cancer is much more serious than basal cell carcinoma and squamous cell carcinoma. It can spread quickly to other organs and causes the vast majority of skin cancer deaths in the United States. Usually melanomas develop in or around an existing mole.
Appearance
Signs and symptoms of melanoma vary depending on the exact type and may include:
- A flat or slightly raised, discolored patch with irregular borders and possible areas of tan, brown, black, red, blue or white
- A firm bump, often black but occasionally blue, gray, white, brown, tan, red or your usual skin tone
- A flat or slightly raised mottled tan, brown or dark brown discoloration
- A black or brown discoloration, usually under the nails, on the palms or on the soles of the feet
See more pictures and get details about different types of melanoma in our dedicated melanoma section.
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Skin Cancer Warning Signs
The main symptom of skin cancer is a mole or other growth on your skin. To find these growths, you need to look for them. Some doctors recommend that you do a full-body self-exam in front of a mirror once a month.
Most skin cancers develop in sun-exposed areas like your face, scalp, chest, arms, and legs so its important to check these areas.
Its also a good idea to check places that are rarely exposed, such as your palms, genitals, your fingernails and toenails, and the soles of your feet.
Skin Cancer Diagnosis Always Requires A Skin Biopsy
When you see a dermatologist because youve found a spot that might be skin cancer, your dermatologist will examine the spot.
If the spot looks like it could be a skin cancer, your dermatologist will remove it all or part of it. This can easily be done during your appointment. The procedure that your dermatologist uses to remove the spot is called a skin biopsy.
Having a skin biopsy is essential. Its the only way to know whether you have skin cancer. Theres no other way to know for sure.
What your dermatologist removes will be looked at under a microscope. The doctor who examines the removed skin will look for cancer cells. If cancer cells are found, your biopsy report will tell you what type of skin cancer cells were found. When cancer cells arent found, your biopsy report will explain what was seen under the microscope.
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Why Does My Skin Feel Like It’s Burning
Burning sensation on the skin can be caused by various conditions some are light and may go away on their own, while some others may be rather serious and need medical care.
1. Anxiety
When a person is anxious, it leads to sensitive skin. This results in the skin becoming easily affected with breakout of rashes and itching. These reactions can be without any significant cause too. Anxiety also leads to stress which acts as a trigger for existing skin ailments like psoriasis, herpes and eczema. In these conditions skin feels like it’s burning.
2. Drugs and Toxins
Burning sensation in the skin can be caused due to drugs and toxins, and this can be seen with or without other symptoms. When such symptoms due to pharmaceuticals are seen, it is called as dermatitis medicamentosa or drug eruptions. Exposure to illicit drugs can cause the receptors and nerves to get irritated, changes in the brain chemistry, along with burning sensation of the skin.
Poison, consumed intentionally or accidentally can cause burning sensation of skin. These poisons or toxins can be naturally occurring or synthetic. Arsenic poisoning, which is used widely in intentional poisoning can cause burning in skin.
3. Trauma
Your skin feels like it’s burning when it has undergone trauma due to the following radiation, insect bite, strong sunlight, burns caused by heat or chemicals, strong injury or impact due to blunt force. The skin will feel red, hot and will be swollen due to inflammation.
4. Allergy
Less Common Skin Cancers
Kaposi’s sarcoma is a rare skin cancer which develops from the skin’s blood vessels and presents as reddish or purplish patches or nodules. It usually may develop in individuals with a weakened immune system, but it can also occur in adults of Mediterranean ancestry.
Merkel cell carcinoma is a rare, aggressive skin cancer of neuroendocrine origin usually occurring in older people. It appears as a flesh-toned or reddish-bluish shiny nodule on the face or head and neck areas.
Sebaceous gland carcinoma is an uncommon, aggressive cancer of the oil glands of the hair follicles. They usually appear as hard, painless nodules most commonly on the eyelids or near the eyelids.
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Basal Cell Nevus Syndrome
This rare inherited condition, which is also known as Gorlin syndrome, increases your risk of developing basal cell cancer, as well as other types of tumors. The disease can cause clusters of basal cell carcinoma, especially on areas like your face, chest, and back. You can learn more about basal cell nevus syndrome here.
How Does Skin Cancer Produce Signs And Symptoms
In skin cancer, the cells DNA is damaged which causes them to mutate and reproduce abnormally. The cells then form a mass of cancer cells that presents as an abnormal bump, lesion or mole.
As the skin cancer spreads along the nerves, it can produce itching, pain and numbness.
Exposure to UV radiation from the sun and from tanning beds is just one factor that can damage cells DNA and lead to skin cancer. The damage to the cells DNA can occur several years before the cancer develops.
Being exposed to certain toxic chemicals and having a weakened immune system are additional factors which can contribute to the development of skin cancer.
Staging describes where the lung cancer is located, if it has spread and whether the tumour is affecting other parts of the body. Stage 0 means there are cancer cells present, yet they havent spread or grown into surrounding cells. Stage 1 means the cancer is 2cm or less and has one or no high risk features . Stage 2 means the cancer is 2cm or more and has 2 or more high risk features. Stages 3-4 mean the cancer has spread to a lymph node or other internal organs and is advanced.
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What The Patient Can Do
- Talk to your cancer care team about your rash and what they recommend to help the rash get better. Your cancer care team may recommend mild soaps, lotions, and moisturizers. In certain cases, your doctor may prescribe medication to help with the rash.
- Clean the skin gently with warm water, gentle soap, and a soft cloth
- Rinse the rash area carefully and pat dry
- Keep your skin moisturized
- Protect the affected area from heat and cold
- Stay out of the sun as much as possible, because sunlight seems to trigger and/or worsen rashes in some people. If youll be outside during the day, wear a hat and clothes with long sleeves. Use a broad-spectrum sunscreen with SPF of at least 30 and zinc oxide or titanium dioxide at least 1 hour before going out. Be careful near windows too.
- Wear loose-fitting, soft clothing.
- Apply medicines prescribed for skin reactions.
- Protect all of your skin from the sun. For instance, wear a wide-brimmed hat, sunglasses, and long-sleeved shirts when outside.
When To See A Healthcare Provider

If you notice any of the signs or symptoms of skin cancer mentioned above, make an appointment to see your healthcare provider. A dermatologist can examine your skin and determine if a biopsy is needed. This is true no matter your skin color.
Skin cancer can more difficult to see or may look different on darker skin, and even healthcare providers can overlook melanomas in people of color. If you are concerned, but do not feel that your concern is being addressed, be your own advocate and continue to ask questions or get a second opinion.
Skin Cancer Doctor Discussion Guide
Get our printable guide for your next doctor’s appointment to help you ask the right questions.
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Biological Therapies And Melanoma
Biological therapies are treatments using substances made naturally by the body. Some of these treatments are called immunotherapy because they help the immune system fight the cancer, or they occur naturally as part of the immune system.
There are many biological therapies being researched and trialled, which in the future may help treat people with melanoma. They include monoclonal antibodies and vaccine therapy.
When To Seek Help
Not all sores on the skin are skin cancer. But if you do develop a skincancer, the earlier it is treated, the better the outcome for you.
Most people find SCCs by checking their own skin. Check your skin regularly so you notice any changes. See a doctor if:
- you have a sore that doesn’t heal in 2 months
- you notice a new and unusual looking spot
- an existing spot changes in colour, size or shape
- you have a spot that is asymmetrical
- you have a spot with an uneven border
- you have a spot with an unusual or uneven colour
- you have a spot that is larger than 7 mm
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What Types Of Skin Cancer Can Cause Itching
When itching is traced to skin cancer, the cancer is usually a non-melanoma type, such as squamous cell carcinoma or, less often, basal cell carcinoma. In general, pain and tenderness are more commonly associated with skin cancer than itchy skin, but cancer can potentially irritate the fine nerve endings in the skin and cause an itching sensation.
An oncologist in the Cutaneous Oncology Program at Moffitt Cancer Center can help you determine if your itchy skin lesion or mole is cancerous. You can request an appointment by calling 1-888-663-3488 or completing our new patient registration form online. Our multispecialty team provides a full range of screening, diagnostic, treatment and supportive care services in one location without the need for referrals.
What Are The Symptoms Of Skin Cancer
Skin cancers first appear as a spot, lump or scaly area on the skin, or a mole that changes colour, size or shape over several weeks or months. These changes can appear anywhere on the body, particularly areas frequently exposed to the sun. Skin cancers may bleed and become inflamed, and can be tender to the touch.
There are certain characteristics to look for in spots and moles. Remember the ‘ABCDE’ of skin cancer when checking your skin:
- Asymmetry does each side of the spot or mole look different to the other?
- Border is it irregular, jagged or spreading?
- Colours are there several, or is the colour uneven or blotchy?
- Diameter look for spots that are getting bigger
- Evolution is the spot or mole changing or growing over time?
Changes may include an area that is scaly, shiny, pale or bright pink in colour, or a spot or lump that grows quickly and is thick, red, scaly or crusted.
See your doctor if you notice any new spots or an existing spot that changes size, shape or colour over several weeks or months. Your doctor can help you distinguish between a harmless spot such as a mole, and a sunspot or irregular mole that could develop later into skin cancer.
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Itch And Pain In Nonmelanoma Skin Cancer: Pain As An Important Feature Of Cutaneous Squamous Cell Carcinoma
Correspondence:
Pain is a common feature of cancer with an estimated prevalence rate between 52% and 77%. Itch is the most common dermatologic symptom and is also a common feature of lymphoma. However, no studies have been performed examining the prevalence rates of pain and itch in common skin cancers. Squamous cell carcinoma and basal cell carcinoma are the 2 most common types of nonmelanoma skin cancer . They have a rapidly increasing incidence in the United States, with nearly 4 million new cases of NMSC diagnosed each year. The purpose of the present study was to assess the prevalence and intensity of pain and itch among the 2 most common skin cancers.
You Can Find Skin Cancer On Your Body
The best way to find skin cancer is to examine yourself. When checking, you want to look at the spots on your skin. And you want to check everywhere from your scalp to the spaces between your toes and the bottoms of your feet.
If possible, having a partner can be helpful. Your partner can examine hard-to-see areas like your scalp and back.
Getting in the habit of checking your skin will help you notice changes. Checking monthly can be beneficial. If you have had skin cancer, your dermatologist can tell you how often you should check your skin.
People of all ages get skin cancer
Checking your skin can help you find skin cancer early when its highly treatable.
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How Is Skin Cancer Diagnosed
Your doctor or dermatologist will first conduct a physical examination by looking at your skin to identify any suspicious spots using a dermatoscope .
Its not always possible to tell from looking at it whether a spot or lump is cancerous or not. So your doctor or dermatologist may take a skin biopsy. This is where part of, or all of, your spot is removed and sent for further study under a microscope.
Some smartphone apps allow you to photograph your skin and compare photos over time. While they can be a good reminder to check your skin and record details, they shouldnt replace a visit to the doctor. See a doctor if youre concerned about any spots or moles on your skin.